water in methanol 24 h; Heating;

1: N-iodosuccinimide / H2SO4 / 21 h / 5 - 20 °C 2: MeONa / methanol / 20 h / 20 °C 3: 37.14 g / aq. HClO4; AcOH; aq. H2O2 / 4 h / 50 °C 4: HCl / 4.5 h / Heating 5: 21.59 g / aq. TiCl3 / methanol / 20 h / 20 °C 6: 35.2 g / pyridinium bromide perbromide / 2-methyl-propan-2-ol / 4 h / 20 °C 7: 16.26 percent / H2O / methanol / 24 h / Heating View Scheme

1: MeONa / methanol / 20 h / 20 °C 2: 37.14 g / aq. HClO4; AcOH; aq. H2O2 / 4 h / 50 °C 3: HCl / 4.5 h / Heating 4: 21.59 g / aq. TiCl3 / methanol / 20 h / 20 °C 5: 35.2 g / pyridinium bromide perbromide / 2-methyl-propan-2-ol / 4 h / 20 °C 6: 16.26 percent / H2O / methanol / 24 h / Heating View Scheme

1: 37.14 g / aq. HClO4; AcOH; aq. H2O2 / 4 h / 50 °C 2: HCl / 4.5 h / Heating 3: 21.59 g / aq. TiCl3 / methanol / 20 h / 20 °C 4: 35.2 g / pyridinium bromide perbromide / 2-methyl-propan-2-ol / 4 h / 20 °C 5: 16.26 percent / H2O / methanol / 24 h / Heating View Scheme

1: pyridinium bromide perbromide / 2-methyl-propan-2-ol / 4 h / 20 °C 2: 16.26 percent / H2O / methanol / 24 h / Heating View Scheme

1: 35.2 g / pyridinium bromide perbromide / 2-methyl-propan-2-ol / 4 h / 20 °C 2: 16.26 percent / H2O / methanol / 24 h / Heating View Scheme

1: HCl / 4.5 h / Heating 2: 21.59 g / aq. TiCl3 / methanol / 20 h / 20 °C 3: 35.2 g / pyridinium bromide perbromide / 2-methyl-propan-2-ol / 4 h / 20 °C 4: 16.26 percent / H2O / methanol / 24 h / Heating View Scheme

1: 22.71 g / aq. TiCl3; NH4OAc / acetone / 5 h / 20 °C 2: pyridinium bromide perbromide / 2-methyl-propan-2-ol / 4 h / 20 °C 3: 16.26 percent / H2O / methanol / 24 h / Heating View Scheme

1: 21.59 g / aq. TiCl3 / methanol / 20 h / 20 °C 2: 35.2 g / pyridinium bromide perbromide / 2-methyl-propan-2-ol / 4 h / 20 °C 3: 16.26 percent / H2O / methanol / 24 h / Heating View Scheme

1: 69 percent / aq. NaOH; aq. H2O2 / pH 8 - 9 2: HCl / 4.5 h / Heating 3: 21.59 g / aq. TiCl3 / methanol / 20 h / 20 °C 4: 35.2 g / pyridinium bromide perbromide / 2-methyl-propan-2-ol / 4 h / 20 °C 5: 16.26 percent / H2O / methanol / 24 h / Heating View Scheme