3-甲基-6-苯基-咪唑并[2,1-b]噻唑合成路线 （共 8 条）
反应条件
1: in acetone 3 h; RefluxInert atmosphere; 2: With hydrogenchloride in water 2 h; RefluxInert atmosphere;
参考文献
Huang, Guoli; Sun, Hongsheng; Qiu, Xiaojie; Jin, Can; Lin, Chen; Shen, Yingzhong; Jiang, Juli; Wang, Leyong
Organic Letters, 2011 , vol. 13, # 19 p. 5224 - 5227
反应条件
1: 81 percent / acetone / 24 h / 20 °C 2: 76 percent / 1M aq. NaHCO3 / CHCl3 / 0.33 h / 20 °C 3: ethanol / 1 h / Heating View Scheme
参考文献
Khazi; Koti; Gadad; Mahajanshetti; Shivakumar; Akki
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2004 , vol. 43, # 2 p. 393 - 398
反应条件
in ethanol 1 h; Heating; Yield given;
参考文献
Meakins, G. Denis; Musk, Sally R.R.; Robertson, Colin A.; Woodhouse, Lee S.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989 , p. 643 - 648
反应条件
hydrogenchloride; potassium hydroxide 1) EtOH, H2O, 2 h, reflux, 2) 2 h, reflux; Yield given. Multistep reaction;
参考文献
Compton, Victoria J.; Meakins, G. Denis; Raybould, Amanda J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 15 p. 2029 - 2032
反应条件
1: 2) aq. NaHCO3 / 1) acetone, reflux, 2) CH2Cl2, 20 deg C 2: 1) KOH, 2) aq. HCl / 1) EtOH, H2O, 2 h, reflux, 2) 2 h, reflux View Scheme
参考文献
Compton, Victoria J.; Meakins, G. Denis; Raybould, Amanda J.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1992 , # 15 p. 2029 - 2032
参考文献
Kotschergin; Schtschukina
Zhurnal Obshchei Khimii, 1956 , vol. 26, p. 458,464; engl. Ausg. S. 483, 488
参考文献
Kondo; Nagasawa
Yakugaku Zasshi, 1937 , vol. 57, p. 1050,1052; dtsch. Ref. S. 308
Chem.Abstr., 1938 , p. 3398
反应条件
(i) HNO3, MeOH, (ii) H2SO4; Multistep reaction;
参考文献
Pyl,T. et al.
Justus Liebigs Annalen der Chemie, 1961 , vol. 643, p. 153 - 160
