4-(4-BOC-哌嗪磺酰基)溴苯合成路线 （共 2 条）
反应条件
triethylamine in dichloromethane T=0 - 20°C; 3 h;
参考文献
F. HOFFMANN-LA ROCHE AG; FIROOZNIA, Fariborz; GILLESPIE, Paul; LIN, Tai-An; MERTZ, Eric; SIDDURI, Achyutharao; SO, Sung-Sau; TAN, Jenny; THAKKAR, Kshitij Chhabilbhai
Patent: WO2010/55005 A1, 2010 ;
Location in patent: Page/Page column 120 ;
WO 2010/055005 A1
反应条件
1: With trifluoroacetic acid in dichloromethane T=20°C; 2: With sodium hydrogencarbonate in dichloromethane; water
参考文献
VERTEX PHARMACEUTICALS INCORPORATED
Patent: WO2004/111014 A1, 2004 ;
Location in patent: Page/Page column 265 ;
WO 2004/111014 A1
