1-(二甲基氨基)-3-(4-硝基苯氧基)-2-丙醇合成路线 （共 4 条）
反应条件
in methanol; N,N-dimethyl-formamide T=20°C;
参考文献
Anderson, Malcolm; Beattie, John F.; Breault, Gloria A.; Breed, Jason; Byth, Kate F.; Culshaw, Janet D.; Ellston, Rebecca P. A.; Green, Stephen; Minshull, Claire A.; Norman, Richard A.; Pauptit, Richard A.; Stanway, Judith; Thomas, Andrew P.; Jewsbury, Philip J.
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 18 p. 3021 - 3026
反应条件
dimethyl amine in methanol; N,N-dimethyl-formamide
参考文献
AstraZeneca AB
Patent: EP1161428 B1, 2003 ;
反应条件
1: 78 percent / K2CO3; Bu4Br / 100 °C 2: 90 percent / methanol; dimethylformamide / 20 °C View Scheme
参考文献
Breault, Gloria A.; Ellston, Rebecca P. A.; Green, Stephen; James, S. Russell; Jewsbury, Philip J.; Midgley, Catherine J.; Pauptit, Richard A.; Minshull, Claire A.; Tucker, Julie A.; Pease, J. Elizabeth
Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 18 p. 2961 - 2966
参考文献
Fourneau
Chem. Zentralbl., 1910 , vol. 81, # I p. 1134
Full Text Show Details
Poulenc Freres; Fourneau
Patent: DE228205 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 10, p. 1173
