4-溴甲基-1-氟-2-碘苯合成路线 （共 3 条）
反应条件
N-bromosuccinmide in tetrachloromethane
参考文献
Pfizer Inc.
Patent: US6150377 A1, 2000 ;
反应条件
N-bromosuccinmide; dibenzoyl peroxide in tetrachloromethane 3 h; Heating;
参考文献
Liu, Gang; Xin, Zhili; Pei, Zhonghua; Hajduk, Philip J.; Abad-Zapatero, Cele; Hutchins, Charles W.; Zhao, Hongyu; Lubben, Thomas H.; Ballaron, Stephen J.; Haasch, Deanna L.; Kaszubska, Wiweka; Rondinone, Cristina M.; Trevillyan, James M.; Jirousek, Michael R.
Journal of Medicinal Chemistry, 2003 , vol. 46, # 20 p. 4232 - 4235
反应条件
sodium hydrogencarbonate in dimethyl sulfoxide T=120°C; 1.5 h;
参考文献
Liu, Gang; Xin, Zhili; Pei, Zhonghua; Hajduk, Philip J.; Abad-Zapatero, Cele; Hutchins, Charles W.; Zhao, Hongyu; Lubben, Thomas H.; Ballaron, Stephen J.; Haasch, Deanna L.; Kaszubska, Wiweka; Rondinone, Cristina M.; Trevillyan, James M.; Jirousek, Michael R.
Journal of Medicinal Chemistry, 2003 , vol. 46, # 20 p. 4232 - 4235
