1,3-苯并噻唑-2-甲腈合成路线 （共 28 条）
参考文献
Busby, Reginald E.; Hussain, Syed M.; Mohamed, Murtedza bin; Parrick, John; Shaw, C. J. Granville; et al.
Journal of Chemical Research, Miniprint, 1980 , # 12 p. 4935 - 4953
反应条件
1: aq. NaOH / 0.17 h / 95 °C 2: 157 °C View Scheme
参考文献
Baudet,P.; Otten,C.
Helvetica Chimica Acta, 1970 , vol. 53, p. 1683 - 1693
参考文献
Baudet,P.; Otten,C.
Helvetica Chimica Acta, 1970 , vol. 53, p. 1683 - 1693
反应条件
n-butyllithium 1) THF, -78 deg C, 30 min, 2) THF, -78 deg C, 30 min then -78 deg C to RT, 2 h; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Nagasaki, Izuru; Suzuki, Yumiko; Iwamoto, Ken-Ichi; Higashino, Takeo; Miyashita, Akira
Heterocycles, 1997 , vol. 46, # 1 p. 443 - 450
反应条件
sulfuric acid; nitric acid T=0°C; 2.75 h;
参考文献
GRYSHUK, Amy L.; Perkins, Julie; LaTour, John V.
Patent: US2011/224442 A1, 2011 ;
Location in patent: Page/Page column 13 ;
反应条件
1.1: nitric acid; sulfuric acid / 2.75 h / 0 °C 2.1: tin(ll) chloride / ethanol / 2 h / 60 °C / Inert atmosphere 2.2: pH 7 View Scheme
参考文献
GRYSHUK, Amy L.; Perkins, Julie; LaTour, John V.
Patent: US2011/224442 A1, 2011 ;
反应条件
hydrogenchloride
Ambient temperature;
参考文献
Baudet,P.; Rao,D.
Helvetica Chimica Acta, 1970 , vol. 53, p. 1011 - 1030
反应条件
hydrogen sulfide in dimethyl sulfoxide
T=20°C;
参考文献
Calderon Ortiz, Lorena K.; Wuerfel, Hendryk; Taeuscher, Eric; Wei, Dieter; Birckner, Eckhard; Goerls, Helmar; Beckert, Rainer
Synthesis (Germany), 2014 , vol. 46, # 1 art. no. SS-2013-T0566-OP, p. 126 - 134
