2-甲基-2-丙基(2R)-2-[(6-硝基-1H-苯并三唑-1-基)硫代甲酰]-1-吡咯烷羧酸酯合成路线 （共 4 条）
反应条件
sodium nitrite in acetic acid T=0°C; 0.5 h;
参考文献
McKeever, Benedict; Pattenden, Gerald
Tetrahedron, 2003 , vol. 59, # 15 p. 2701 - 2712
反应条件
1.1: isobutyl chloroformate; N-methylmorpholine / tetrahydrofuran / 0.33 h / -20 °C 1.2: 81 percent / tetrahydrofuran / -20 - 20 °C 2.1: 95 percent / P4S10; Na2CO3 / tetrahydrofuran / 3 h / 0 - 20 °C 3.1: NaNO2 / acetic acid / 0.5 h / 0 °C View Scheme
参考文献
McKeever, Benedict; Pattenden, Gerald
Tetrahedron, 2003 , vol. 59, # 15 p. 2701 - 2712
反应条件
1.1: isobutyl chloroformate; N-methylmorpholine / tetrahydrofuran / 0.33 h / -20 °C 1.2: 81 percent / tetrahydrofuran / -20 - 20 °C 2.1: 95 percent / P4S10; Na2CO3 / tetrahydrofuran / 3 h / 0 - 20 °C 3.1: NaNO2 / acetic acid / 0.5 h / 0 °C View Scheme
参考文献
McKeever, Benedict; Pattenden, Gerald
Tetrahedron, 2003 , vol. 59, # 15 p. 2701 - 2712
反应条件
1: 95 percent / P4S10; Na2CO3 / tetrahydrofuran / 3 h / 0 - 20 °C 2: NaNO2 / acetic acid / 0.5 h / 0 °C View Scheme
参考文献
McKeever, Benedict; Pattenden, Gerald
Tetrahedron, 2003 , vol. 59, # 15 p. 2701 - 2712
