甲基N-[3-[3-[2-[4-氨基甲酰-5-(氨基甲酰氨基)噻吩-2-基]乙炔基]苯胺基]-3-氧代丙基]氨基甲酸酯合成路线 （共 3 条）
反应条件
sodium hydroxide; bromine in ethanol; water
参考文献
Shell Oil Company
Patent: US4778577 A1, 1988 ;
反应条件
potassium hydroxide; phosphoric acid; ammonium formate; palladium on charcoal in methanol; water
参考文献
Shell Oil Company
Patent: US4812581 A1, 1989 ;
反应条件
With hydrogen; palladium dihydroxide in methanol T=20°C;
参考文献
Evans, Gary B.; Furneaux, Richard H.; Greatrex, Ben; Murkin, Andrew S.; Schramm, Vern L.; Tyler, Peter C. Journal of Medicinal Chemistry, 2008 , vol. 51, # 4 p. 948 - 956
