4-[(叔丁氧酰胺基)甲基]吡啶-2-羧酸[激子手性法用试剂]合成路线 （共 5 条）
反应条件
sodium hydroxide in ethanol Hydrolysis; 24 h; Heating;
参考文献
Huang, Xuefei; Borhan, Babak; Rickman, Barry H.; Nakanishi, Koji; Berova, Nina
Chemistry - A European Journal, 2000 , vol. 6, # 2 p. 216 - 224
反应条件
1: 96 percent / Et3N / tetrahydrofuran / 20 °C 2: 82 percent / m-CPBA / CH2Cl2 / 12 h / 20 °C 3: 53 percent / dimethylcarbamyl chloride / CH2Cl2 / 48 h / 20 °C 4: 100 percent / aq. NaOH / ethanol / 24 h / Heating View Scheme
参考文献
Huang, Xuefei; Borhan, Babak; Rickman, Barry H.; Nakanishi, Koji; Berova, Nina
Chemistry - A European Journal, 2000 , vol. 6, # 2 p. 216 - 224
反应条件
1: 96 percent / Et3N / tetrahydrofuran / 20 °C 2: 82 percent / m-CPBA / CH2Cl2 / 12 h / 20 °C 3: 53 percent / dimethylcarbamyl chloride / CH2Cl2 / 48 h / 20 °C 4: 100 percent / aq. NaOH / ethanol / 24 h / Heating View Scheme
参考文献
Huang, Xuefei; Borhan, Babak; Rickman, Barry H.; Nakanishi, Koji; Berova, Nina
Chemistry - A European Journal, 2000 , vol. 6, # 2 p. 216 - 224
反应条件
1: 82 percent / m-CPBA / CH2Cl2 / 12 h / 20 °C 2: 53 percent / dimethylcarbamyl chloride / CH2Cl2 / 48 h / 20 °C 3: 100 percent / aq. NaOH / ethanol / 24 h / Heating View Scheme
参考文献
Huang, Xuefei; Borhan, Babak; Rickman, Barry H.; Nakanishi, Koji; Berova, Nina
Chemistry - A European Journal, 2000 , vol. 6, # 2 p. 216 - 224
反应条件
1: 53 percent / dimethylcarbamyl chloride / CH2Cl2 / 48 h / 20 °C 2: 100 percent / aq. NaOH / ethanol / 24 h / Heating View Scheme
参考文献
Huang, Xuefei; Borhan, Babak; Rickman, Barry H.; Nakanishi, Koji; Berova, Nina
Chemistry - A European Journal, 2000 , vol. 6, # 2 p. 216 - 224
