3,5-二(三氟甲基)苯-1-碳酰肼合成路线 （共 3 条）
反应条件
hydrazine hydrate in methanol T=40°C; 16 h; Inert atmosphere;
参考文献
Tsuchiya, Kousuke; Kasuga, Hidemasa; Kawakami, Akira; Taka, Hideo; Kita, Hiroshi; Ogino, Kenji
Journal of Polymer Science, Part A: Polymer Chemistry, 2010 , vol. 48, # 7 p. 1461 - 1468
反应条件
1: With 4-methyl-morpholine; isobutyl chloroformate in tetrahydrofuran T=20°C; 1.5 h; 2: With hydrazine in tetrahydrofuran 5 h;
参考文献
Hoffmann-La Roche Inc.
Patent: US6265426 B1, 2001 ;
US 6265426 B1
反应条件
hydrazine hydrate in ethanol T=80°C;
参考文献
Wang, Danzhu; Chen, Weixuan; Zheng, Yueqin; Dai, Chaofeng; Wang, Lifang; Wang, Binghe
Heterocyclic Communications, 2013 , vol. 19, # 3 p. 171 - 177
