N-乙基-2-氨甲基吡咯烷合成路线 （共 34 条）
反应条件
sodium bis(2-methoxyethoxy)aluminium dihydride in tetrahydrofuran; toluene T=0 - 70°C;
参考文献
AUSPEX PHARMACEUTICALS, INC.
Patent: US2010/105755 A1, 2010 ;
Location in patent: Page/Page column 12 ;
US 20100105755 A1
参考文献
Reitsema
Journal of the American Chemical Society, 1949 , vol. 71, p. 2041
反应条件
palladium on activated charcoal Hydrogenation;
参考文献
Reitsema
Journal of the American Chemical Society, 1949 , vol. 71, p. 2041
反应条件
1: SOCl2 / CHCl3 / 4.5 h / 0 °C 2: NaN3, KI / dimethylformamide / 8 h 3: LiAlH4 / diethyl ether / 8 h View Scheme
参考文献
Bishop; Mathis; Gerdes; Whitney; Eaton; Mailman
Journal of Medicinal Chemistry, 1991 , vol. 34, # 5 p. 1612 - 1624
反应条件
1: NaN3, KI / dimethylformamide / 8 h 2: LiAlH4 / diethyl ether / 8 h View Scheme
参考文献
Bishop; Mathis; Gerdes; Whitney; Eaton; Mailman
Journal of Medicinal Chemistry, 1991 , vol. 34, # 5 p. 1612 - 1624
反应条件
1: K2CO3 / CH2Cl2 / 1.5 h 2: SOCl2 / CHCl3 / 4.5 h / 0 °C 3: NaN3, KI / dimethylformamide / 8 h 4: LiAlH4 / diethyl ether / 8 h View Scheme
参考文献
Bishop; Mathis; Gerdes; Whitney; Eaton; Mailman
Journal of Medicinal Chemistry, 1991 , vol. 34, # 5 p. 1612 - 1624
参考文献
Lilly S.A.; Lilly Industries Limited
Patent: US5021449 A1, 1991 ;
US 5021449 A
参考文献
Yamanouchi Pharmaceutical Co., Ltd.
Patent: US4041032 A1, 1977 ;
参考文献
Yamanouchi Pharmaceutical Co., Ltd.
Patent: US4041032 A1, 1977 ;
参考文献
Yamanouchi Pharmaceutical Co., Ltd.
Patent: US4041032 A1, 1977 ;
