反应条件
1: 1.) BuLi
2: SOCl2, MgSO4 / 10 h / 50 °C
3: 75 percent / 2N aq. NaOH / 25 °C / pig liver esterase
4: Et3N / tetrahydrofuran / 0.25 h / -15 °C
5: NaBH4, MeOH / tetrahydrofuran / 2 h / 0 °C
6: 1.) (COCl)2, DMSO, 2.) Et3N / 1.) CH2Cl2, -60 deg C
7: 1.) LiCl, DBU / 1.) MeCN, RT, 1 h, 2.) MeCN, RT, 4 h
View Scheme
参考文献
Fadel; Garcia-Argote
Tetrahedron Asymmetry, 1996 , vol. 7, # 4 p. 1159 - 1166
