2,1-(4,5,6,7-四氢苯并)异恶唑-3-羧酸合成路线 （共 4 条）
反应条件
sulfuric acid; hydroxylamine hydrochloride T=100°C; Cyclization; hydrolysis; 12 h;
参考文献
Martins, Marcos A. P.; Flores, Alex F. C.; Bastos, Giovani P.; Sinhorin, Adilson; Bonacorso, Helio G.; Zanatta, Nilo
Tetrahedron Letters, 2000 , vol. 41, # 3 p. 293 - 297
反应条件
1.1: pyridine / CHCl3 / 10 h / 50 °C 1.2: 95 percent / sulfuric acid / H2O; CHCl3 / 2 h / 80 °C 2.1: hydroxylamine hydrochloride / methanol / 10 h / 40 °C 3.1: sulfuric acid / H2O / 75 - 100 °C View Scheme
参考文献
Martins, Marcos A.P.; Brondani, Sergio; Leidens, Victor L.; Flores, Darlene C.; Moura, Sidnei; Zanatta, Nilo; Hoerner, Manfredo; Flores, Alex F.C.
Canadian Journal of Chemistry, 2005 , vol. 83, # 8 p. 1171 - 1177
反应条件
sulfuric acid Hydrolysis; Heating;
参考文献
Martins, Marcos A. P.; Flores, Alex F. C.; Bastos, Giovani P.; Sinhorin, Adilson; Bonacorso, Helio G.; Zanatta, Nilo
Tetrahedron Letters, 2000 , vol. 41, # 3 p. 293 - 297
反应条件
hydrogenchloride; ethanol; hydroxylamine Erhitzen des Reaktionsprodukts mit wss. NaOH;
参考文献
Basu; Dhar
Journal of the Indian Chemical Society, 1946 , vol. 23, p. 189,191
