1: K3Fe(CN)6; K2CO3; OsO4 / (DHQD)2-PHAL / 2-methyl-propan-2-ol; H2O / 24 h / 0 °C 2: 96 percent / pyridine / 18 h / 20 °C 3: ethanol; H2O / 18 h / 20 °C 4: 3N aq. NaOH / 3 h / 70 °C 5: HCl; PTSA / methanol; acetone / 8 h / 20 °C / pH 2 View Scheme

1: K3Fe(CN)6; K2CO3; OsO4 / (DHQD)2-PHAL / 2-methyl-propan-2-ol; H2O / 24 h / 0 °C 2: SOCl2; Et3N / CH2Cl2 / 0.33 h / 0 °C 3: NaIO4; RuCl3*H2O / dimethylsulfoxide; acetonitrile; H2O / 2 h / 0 °C 4: dimethylformamide / 8 h / 80 °C 5: aq. H2SO4 / ethanol / 18 h / Heating View Scheme