2-甲氧基异烟酸甲酯合成路线

参考文献

AstraZeneca AB; NPS PHARMACEUTICALS, INC.
Patent: US2007/259926 A1, 2007 ;
Location in patent: Page/Page column 13 ;
US 20070259926 A1

22282-72-02-羟基异烟酸+

74-88-4甲基碘

26156-51-42-甲氧基异烟酸甲酯

参考文献

MERCK SHARP and DOHME CORP.; KUDUK, Scott, D.; CHANG, Ronald, K.; GRESHOCK, Thomas, J.
Patent: WO2011/25851 A1, 2011 ;
Location in patent: Page/Page column 71 ;
WO 2011/025851 A1

58481-11-12-氯异烟酸甲酯

26156-51-42-甲氧基异烟酸甲酯

参考文献

Pharmacia Corporation
Patent: US6509361 B1, 2003 ;
US 6509361 B1

58481-11-12-氯异烟酸甲酯+

124-41-4甲醇钠

26156-51-42-甲氧基异烟酸甲酯

参考文献

Adger, Brian M.; Bannister, Robin; Lewis, Norman J.; O'Farrell, Clare
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1988 , p. 2785 - 2790

2459-09-8异烟酸甲酯

586-95-84-吡啶甲醇+

26156-51-42-甲氧基异烟酸甲酯+

58481-17-72-羟基甲基异烟酸甲酯+

82828-86-2

参考文献

Sugiyama, Toru; Kusano, Yukari; Yagi, Kazuya; Ito, Yoko; Sugimori, Akira
Bulletin of the Chemical Society of Japan, 1984 , vol. 57, # 7 p. 1882 - 1886

67-56-1甲醇+

2459-09-8异烟酸甲酯

26156-51-42-甲氧基异烟酸甲酯+

58481-17-72-羟基甲基异烟酸甲酯

参考文献

Sugiyama, Toru; Yagi, Kazuya; Ito, Yoko; Sugimori, Akira
Chemistry Letters, 1982 , p. 917 - 920

6313-54-82-氯异烟酸

26156-51-42-甲氧基异烟酸甲酯

参考文献

Adger, Brian M.; Bannister, Robin; Lewis, Norman J.; O'Farrell, Clare
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1988 , p. 2785 - 2790

42521-09-52,6-二氯异烟酸甲酯

26156-51-42-甲氧基异烟酸甲酯

参考文献

Isler et al.
Helvetica Chimica Acta, 1955 , vol. 38, p. 1046,1058

26156-51-42-甲氧基异烟酸甲酯

72716-87-12-甲氧基-4-吡啶甲醛

参考文献

Subramanyam; Noguchi; Weinreb
Journal of Organic Chemistry, 1989 , vol. 54, # 23 p. 5580 - 5585

26156-51-42-甲氧基异烟酸甲酯

105596-63-22-甲氧基-4-吡啶甲酸

参考文献

Isler et al.
Helvetica Chimica Acta, 1955 , vol. 38, p. 1046,1058