1-苯并[b]噻吩-3-基-2-溴乙基-1-酮合成路线 (共 4 条)
反应条件
copper(ll) bromide in chloroform; ethyl acetate 3 h; Reflux;
参考文献
CSPC Zhongqi Pharmaceutical Technology (Shijiazhuang) Co., Ltd.; Shanghai Institute of Pharmaceutical Industry
Patent: EP2311828 A1, 2011 ;
Location in patent: Page/Page column 9 ;
反应条件
1: 50 percent / stannous chloride / benzene / 1 h / 0 °C 2: 48 percent / Br2 / CCl4 / 1 h / Heating View Scheme
参考文献
Nakib, Tahsin Al; Meegan, Mary J.; Burke, M. Louise
Journal of Chemical Research, Miniprint, 1994 , # 5 p. 1042 - 1059
参考文献
Imperial Chemical Industries, PLC
Patent: US4489073 A1, 1984 ;
反应条件
1: sodium ethylate; ethanol
2: phosphorus (V)-oxide; 1,2-dichloro-benzene
View Scheme
参考文献
Pandya et al.
Journal of Scientific and Industrial Research, 1959 , vol. 18 B, p. 516,519