N-(4-溴苯基)甲酰胺合成路线 （共 37 条）
反应条件
sodium hydroxide; tetra-(n-butyl)ammonium iodide; bis(benzonitrile)palladium(II) dichloride; triphenylphosphine in xylene T=90°C; Carbonylation; 4 h;
参考文献
Lapidus; Petrovskii; Bruk; Beletskaya
Russian Journal of Organic Chemistry, 1999 , vol. 35, # 11 p. 1636 - 1639
反应条件
dimethylsulfide borane complex in tetrahydrofuran 3 h; Heating; Yield given;
参考文献
GLAXO GROUP LIMITED
Patent: WO2003/99786 A2, 2003 ;
Location in patent: Page 45 ;
反应条件
bis-[(trifluoroacetoxy)iodo]benzene in 1,2-dichloro-ethane 0.0333333 h; Molecular sieveInert atmosphere;
参考文献
Reddy, N. Veera; Prasad, K. Rajendra; Reddy, P. Sudhir; Lakshmi Kantam; Reddy, K. Rajender
Organic and Biomolecular Chemistry, 2014 , vol. 12, # 14 p. 2172 - 2175
反应条件
in tetrahydrofuran; methanol; water
参考文献
US2003/144274 A1, ;
US 20030144274 A1
反应条件
1: bis-[(trifluoroacetoxy)iodo]benzene / 1,2-dichloro-ethane / 0.03 h / |Molecular sieve; |Inert atmosphere 2: 1,2-dichloro-ethane / 1 h / 60 °C / |Molecular sieve; |Inert atmosphere View Scheme
参考文献
Reddy, N. Veera; Prasad, K. Rajendra; Reddy, P. Sudhir; Lakshmi Kantam; Reddy, K. Rajender
Organic and Biomolecular Chemistry, 2014 , vol. 12, # 14 p. 2172 - 2175
反应条件
1: C7H6BrNO With tris-(dibenzylideneacetone)dipalladium(0); Josiphos-CyPF-t-Bu in toluene
T=20°C; 0.0833333 h; Inert atmosphere;
2: thiolacetic acid potassium salt in toluene
T=110°C; 24 h; Inert atmosphere;
参考文献
Van Den Hoogenband, Adri; Lange, Jos H. M.; Bronger, Raymond P. J.; Stoit, Axel R.; Terpstra, Jan Willem
Tetrahedron Letters, 2010 , vol. 51, # 52 p. 6877 - 6881
反应条件
1: bis-[(trifluoroacetoxy)iodo]benzene / 1,2-dichloro-ethane / 0.03 h / |Molecular sieve; |Inert atmosphere
2: 1,2-dichloro-ethane / 1 h / 60 °C / |Molecular sieve; |Inert atmosphere
View Scheme
参考文献
Reddy, N. Veera; Prasad, K. Rajendra; Reddy, P. Sudhir; Lakshmi Kantam; Reddy, K. Rajender
Organic and Biomolecular Chemistry, 2014 , vol. 12, # 14 p. 2172 - 2175
