Foliamenthoic acid; (E,E)-8-羟基-2,6-二甲基-2,6-辛二烯酸合成路线 （共 7 条）
反应条件
1: With methanol; water; potassium carbonate T=20°C; 2: With hydrogenchloride; water in methanol; dichloromethane pH=3;
参考文献
HAWAII BIOTECH, INC.; LOCKWOOD, Samuel, F.; TANG, Peng, Cho; NADOLSKI, Geoff; FANG, Zhiqiang; DU, Yishu; GEISS, William; WILLIAMS, Richard; BURDICK, William
Patent: WO2006/39685 A2, 2006 ;
Location in patent: Page/Page column 54 ;
反应条件
β-glucosidase from almond; water T=37°C; 24 h; Enzymatic reaction;
参考文献
Morikawa, Toshio; Pan, Yingni; Ninomiya, Kiyofumi; Imura, Katsuya; Yuan, Dan; Yoshikawa, Masayuki; Hayakawa, Takao; Muraoka, Osamu
Chemical and Pharmaceutical Bulletin, 2010 , vol. 58, # 10 p. 1403 - 1407
反应条件
1: 1.) SeO2, salicylic acid, 70percent aq. t-BuOOH, 2.) pyridinium chlorochromate (PCC), AcONa / 1.) CH2Cl2, RT, overnight, 2.) CH2Cl2, 30 min 2: 7.4 g / 2-methyl 2-butene, aq. NaClO2, aq. NaH2PO4*2H2O / 2-methyl-propan-2-ol / 2 h View Scheme
参考文献
Jackson, Henry L.; Nadolski, Geoffry T.; Braun, Cristi; Lockwood, Samuel F.
Organic Process Research and Development, 2005 , vol. 9, # 6 p. 830 - 836
反应条件
sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene in tert-butyl alcohol 2 h;
参考文献
Kato, Tadahiro; Hirano, Takumi; Hoshikawa, Masahiro; Uyehara, Tadao
Bulletin of the Chemical Society of Japan, 1996 , vol. 69, # 1 p. 221 - 228
反应条件
hydrogenchloride in methanol; water 5 h; Heating;
参考文献
Mahato; Pal; Nandy
Tetrahedron, 1992 , vol. 48, # 32 p. 6717 - 6728
反应条件
potassium hydroxide in ethanol 4 h; Heating;
参考文献
Mahato; Pal; Nandy
Tetrahedron, 1992 , vol. 48, # 32 p. 6717 - 6728
反应条件
sodium hydroxide; silver nitrate in ethanol; water 3 h; Ambient temperature; Yield given. Title compound not separated from byproducts;
参考文献
Morimoto; Kurimoto; Imada
Chemical and Pharmaceutical Bulletin, 1985 , vol. 33, # 8 p. 3182 - 3186
