1: With sodium hydride in tetrahydrofuran
T=0°C; 6.3 h; Heating / reflux;
2: With hydrogenchloride; water
T=110°C; 48 h;
3: With sodium hydroxide; water
T=0°C;
参考文献
Apodaca, Richard; Barbier, Ann J.; Carruthers, Nicholas I.; Gomez, Leslie A.; Keith, John M.; Lovenberg, Timothy W.; Wolin, Ronald L.
Patent: US2006/293316 A1, 2006 ;
Location in patent: Page/Page column 18 ;
US 20060293316 A1