1: With sodium hydrogensulfite in water; N,N-dimethyl-formamide T=0°C; 0.5 h; 2: With potassium hydroxide in water; N,N-dimethyl-formamide 0.5 h; 3: With iodine in water; N,N-dimethyl-formamide 0.5 h;
参考文献
Agouron Pharmaceuticals, Inc.
Patent: US2006/94881 A1, 2006 ;
Location in patent: Page/Page column 22 ;
US 20060094881 A1