2-氯-N-[2-[(2-氯乙酰基)氨基]乙基]乙酰胺合成路线 （共 8 条）
反应条件
potassium carbonate in chloroform; water T=0 - 20°C; 5 h;
参考文献
Tanwar, Jyoti; Datta, Anupama; Tiwari, Anjani Kumar; Thirumal, Meganathan; Chuttani, Krishna; Mishra, Anil Kumar
Bioconjugate Chemistry, 2011 , vol. 22, # 2 p. 244 - 255
反应条件
in methanol T=20°C; 10 h;
参考文献
Bioorganic and Medicinal Chemistry, , vol. 21, # 1 p. 278 - 282
参考文献
Zhurnal Organicheskoi Khimii, , vol. 7, p. 1159 - 1162,1192 - 1195
反应条件
in N,N-dimethyl-formamide 0.0833333 h; Heating;
参考文献
Elwahy, Ahmed H.M.; Abbas, Ashraf A.; Kassab, Refaie M.
Heteroatom Chemistry, 2003 , vol. 14, # 6 p. 551 - 559
反应条件
potassium tert-butylate 1.) DMF, 60 deg C, 1 h, 2.) DMF, 80 deg C, overnight; Yield given. Multistep reaction;
参考文献
Lindoy, Leonard F.; Mahendran, Sumathi; Krakowiak, Krzysztof E.; An, Haoyun; Bradshaw, Jerald S.
Journal of Heterocyclic Chemistry, 1992 , vol. 29, # 1 p. 141 - 144
反应条件
sodium methylate in methanol
20 h; Heating;
参考文献
Lin; Figueira; Alt
1984 , vol. 116, # 2 p. 217 - 221
反应条件
2: H2O / Heating
3: aq. HCl / Heating
View Scheme
参考文献
Svetkin,Yu.V. et al.
J. Gen. Chem. USSR (Engl. Transl.), 1976 , vol. 46, p. 2111 - 2117,2031 - 2036
反应条件
2: H2O / Heating
View Scheme
参考文献
Svetkin,Yu.V. et al.
J. Gen. Chem. USSR (Engl. Transl.), 1976 , vol. 46, p. 2111 - 2117,2031 - 2036
