2,3-二氢-2-苯基-1H-吲哚合成路线 （共 28 条）
反应条件
1: 2-phenyl-2,3-dihydro-1H-indole With n-butyllithium in tetrahydrofuran; hexane T=-78°C; 0.5 h; Inert atmosphere; 2: methyl iodide in tetrahydrofuran; hexane T=-78 - 20°C; Inert atmosphere;
参考文献
Saito, Kodai; Shibata, Yukihiro; Yamanaka, Masahiro; Akiyama, Takahiko
Journal of the American Chemical Society, 2013 , vol. 135, # 32 p. 11740 - 11743
反应条件
C21H21ClIrNO2 in tetrahydrofuran; 2,2,2-trifluoroethanol 20 h; Inert atmosphere;
参考文献
Wu, Jianjun; Talwar, Dinesh; Johnston, Steven; Yan, Ming; Xiao, Jianliang
Angewandte Chemie - International Edition, 2013 , vol. 52, # 27 p. 6983 - 6987
Ross. Khim. Zh., 2013 , vol. 125, # 27 p. 7121 - 7125,5
反应条件
Fremy’s salt; acetone in gepufferter wss. Loesung <pH 7>;
参考文献
Teuber; Staiger
Chemische Berichte, 1956 , vol. 89, p. 489,497
反应条件
T=50°C; 19 h; Molecular sieve;
参考文献
Journal of the American Chemical Society, , vol. 135, # 32 p. 11740 - 11743
反应条件
hydrogenchloride; tin in ethanol; water
T=20 - 90°C; 4 h; Inert atmosphere;
参考文献
Saito, Kodai; Shibata, Yukihiro; Yamanaka, Masahiro; Akiyama, Takahiko
Journal of the American Chemical Society, 2013 , vol. 135, # 32 p. 11740 - 11743
反应条件
1: With bis(η4-1,5-cyclooctadiene)-di-μ-methoxy-diiridium(I) in benzene
T=25°C; 16 h; Inert atmosphere;
2: With silica gel
参考文献
Sun, Ke; Sachwani, Rachna; Richert, Kathleen J.; Driver, Tom G.
Organic Letters, 2009 , vol. 11, # 16 p. 3598 - 3601
反应条件
Fe(F20TPP)Cl in 1,2-dichloro-ethane
14 h; Molecular sieveRefluxInert atmosphere;
参考文献
Liu, Yungen; Wei, Jinhu; Che, Chi-Ming
Chemical Communications, 2010 , vol. 46, # 37 p. 6926 - 6928
反应条件
1: 1.) 6 N H2SO4, aq. NaNO2, 2.) aq. NaN3 / 1.) dioxane, 0-5 deg C, 2 h, 2.) r.t., 2 h
2: 9 percent / Irradiation
View Scheme
参考文献
Murata, Shigeru; Yoshidome, Ryuichi; Satoh, Youji; Kato, Noriyasu; Tomioka, Hideo
Journal of Organic Chemistry, 1995 , vol. 60, # 5 p. 1428 - 1434
反应条件
in 1,3,5-trimethyl-benzene
T=120°C; 16 h; Inert atmosphere;
参考文献
Sun, Ke; Sachwani, Rachna; Richert, Kathleen J.; Driver, Tom G.
Organic Letters, 2009 , vol. 11, # 16 p. 3598 - 3601
反应条件
1.1: bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diethylamine / N,N-dimethyl acetamide / 1 h / 20 °C
1.2: 140 °C
2.1: sodium cyanoborohydride / acetic acid / 20 h / 20 °C
View Scheme
参考文献
Yu, Xufen; Park, Eun-Jung; Kondratyuk, Tamara P.; Pezzuto, John M.; Sun, Dianqing
Organic and Biomolecular Chemistry, 2012 , vol. 10, # 44 p. 8835 - 8847
