乙基4-(2-氯乙酰氨基)苯酸合成路线 （共 8 条）
反应条件
potassium carbonate in chloroform 10 h; Reflux;
参考文献
Behbehani, Haider; Ibrahim, Hamada Mohamed
Molecules, 2012 , vol. 17, # 6 p. 6362 - 6385
反应条件
1.1: aq. sulfuric acid / 6 h / Heating 1.2: 75 percent / aq. NH3 2.1: 85 percent / diethyl ether / 3 h / 18 - 20 °C View Scheme
参考文献
Murza; Safarov
Russian Journal of Organic Chemistry, 2000 , vol. 36, # 8 p. 1201 - 1203
参考文献
Takeda; Kuroda
Yakugaku Zasshi, 1925 , # 515 p. 4
Chem. Zentralbl., 1925 , vol. 96, # I p. 2304
参考文献
Otsuka Pharmaceuticals Co., Ltd.
Patent: US6335327 B1, 2002 ;
Location in patent: Page column 116 ;
参考文献
Takeda; Kuroda
Yakugaku Zasshi, 1925 , # 515 p. 4
Chem. Zentralbl., 1925 , vol. 96, # I p. 2304
参考文献
Einhorn
Patent: DE106502 ;
反应条件
potassium carbonate in acetone
Heating;
参考文献
Misra; Barthwal; Parmar; Singh; Stenberg
Journal of Pharmaceutical Sciences, 1976 , vol. 65, # 3 p. 405 - 408
反应条件
1: K2CO3 / acetone / Heating
2: N2H4*H2O / ethanol / Heating
View Scheme
参考文献
Misra; Barthwal; Parmar; Singh; Stenberg
Journal of Pharmaceutical Sciences, 1976 , vol. 65, # 3 p. 405 - 408
