4-氨基甲基-1-甲基哌啶-4-醇合成路线 （共 3 条）
反应条件
hydrogen in methanol P=760.051 Torr; 16 h;
参考文献
TOLERO PHARMACEUTICALS, INC.; XU, Yong; BRENNING, Benjamin, Gary; KULTGEN, Steven, G.; LIU, Xiaohui; SAUNDERS, Michael; HO, Koc-Kan
Patent: WO2013/13188 A1, 2013 ;
Location in patent: Paragraph 00329 ;
WO 2013/013188 A1
反应条件
1: With lithium aluminium tetrahydride in tetrahydrofuran T=0 - 5°C; Heating; 2: With Potassium sodium tartrate in tetrahydrofuran T=20°C; 8 h;
参考文献
SHANGHAI HENGRUI PHARMACEUTICAL CO. LTD.
Patent: WO2007/85188 A1, 2007 ;
Location in patent: Page/Page column 155-156 ;
WO 2007/085188 A1
反应条件
1: sodium methylate / ethanol / 48 h / 20 °C 2: hydrogen / methanol / 16 h / 760.05 Torr View Scheme
参考文献
TOLERO PHARMACEUTICALS, INC.; XU, Yong; BRENNING, Benjamin, Gary; KULTGEN, Steven, G.; LIU, Xiaohui; SAUNDERS, Michael; HO, Koc-Kan
Patent: WO2013/13188 A1, 2013 ;
WO 2013/013188 A1
