1: 4-iodo-3,6-dimethoxypyridazine With isopropylmagnesium chloride in tetrahydrofuran T=20°C; Metallation; 0.5 h; 2: [(Cyanocarbonyl)oxy]ethane in tetrahydrofuran T=20°C; Substitution; hydrolysis; protonation; 1 h;

1: 4-iodo-3,6-dimethoxypyridazine With isopropylmagnesium chloride in tetrahydrofuran T=20°C; Metallation; 0.5 h; 2: chloro-trimethyl-silane in tetrahydrofuran T=20°C; Substitution; hydrolysis; protonation; 1 h;

1: 4-iodo-3,6-dimethoxypyridazine With isopropylmagnesium chloride in tetrahydrofuran T=20°C; Metallation; 0.5 h; 2: benzaldehyde in tetrahydrofuran T=20°C; Substitution; Grignard reaction; hydrolysis; protonation; 1 h;