三氟甲烷磺酸4-甲基-2-(三甲基硅基)苯酯合成路线 （共 25 条）
反应条件
1: 3-bromo-4-hydroxytoluene; 1,1,1,3,3,3-hexamethyl-disilazane in tetrahydrofuran 2 h; RefluxInert atmosphere; 2: With n-butyllithium in tetrahydrofuran; pentane T=-100 - -80°C; 0.333333 h; Inert atmosphere; 3: trifluoromethylsulfonic anhydride in tetrahydrofuran; diethyl ether; pentane T=-100 - -80°C; 0.333333 h; Inert atmosphere;
参考文献
Biju, Akkattu T.; Glorius, Frank
Angewandte Chemie - International Edition, 2010 , vol. 49, # 50 p. 9761 - 9764
反应条件
1: (2-bromo-4-methyl-phenoxy)-trimethyl-silane With n-butyllithium in tetrahydrofuran T=-100 - -80°C; 0.333333 h; 2: trifluoromethylsulfonic anhydride in tetrahydrofuran T=-100 - -80°C; 0.333333 h;
参考文献
Pena, Diego; Cobas, Agustin; Perez, Dolores; Guitian, Enrique
Synthesis, 2002 , # 10 p. 1454 - 1458
反应条件
cesium fluoride; dodecacarbonyl tetracobalt in acetonitrile T=60°C; P=7600.51 Torr; 12 h; Title compound not separated from byproducts.;
参考文献
Chatani; Kamitani; Oshita; Fukumoto; Murai
Journal of the American Chemical Society, 2001 , vol. 123, # 50 p. 12686 - 12687
反应条件
cesium fluoride Title compound not separated from byproducts.;
参考文献
Beltran-Rodil, Sandra; Pena, Diego; Guitian, Enrique
Synlett, 2007 , # 8 p. 1308 - 1310
反应条件
potassium fluoride; 18-crown-6 ether in tetrahydrofuran T=20°C; 24 h; Title compound not separated from byproducts.;
参考文献
Jin, Tienan; Yang, Fan; Yamamoto, Yoshinori
Collection of Czechoslovak Chemical Communications, 2009 , vol. 74, # 6 p. 957 - 972
反应条件
potassium fluoride; 18-crown-6 ether; 3-(2,4,6-trimethyl-phenyl)-5,6,7,8-tetrahydro-4H-cycloheptathiazol-3-ium perchlorate; potassium tert-butylate in tetrahydrofuran T=25°C; 4 h; Inert atmosphere;
参考文献
Biju, Akkattu T.; Glorius, Frank
Angewandte Chemie - International Edition, 2010 , vol. 49, # 50 p. 9761 - 9764
反应条件
cesium fluoride Title compound not separated from byproducts.;
参考文献
Beltran-Rodil, Sandra; Pena, Diego; Guitian, Enrique
Synlett, 2007 , # 8 p. 1308 - 1310
反应条件
cesium fluoride Title compound not separated from byproducts.;
参考文献
Beltran-Rodil, Sandra; Pena, Diego; Guitian, Enrique
Synlett, 2007 , # 8 p. 1308 - 1310
反应条件
potassium fluoride; 18-crown-6 ether; 3-(2,4,6-trimethyl-phenyl)-5,6,7,8-tetrahydro-4H-cycloheptathiazol-3-ium perchlorate; potassium tert-butylate in tetrahydrofuran T=25°C; 4 h; Inert atmosphere;
参考文献
Angewandte Chemie - International Edition, , vol. 49, # 50 p. 9761 - 9764
反应条件
1: With cesium fluoride in toluene; acetonitrile T=110°C; 48 h; Inert atmosphereSealed vial; 2: With trifluoroacetic acid T=20°C; 0.333333 h;
参考文献
Pirali, Tracey; Zhang, Fengzhi; Miller, Anna H.; Head, Jenna L.; McAusland, Donald; Greaney, Michael F.
Angewandte Chemie - International Edition, 2012 , vol. 51, # 4 p. 1006 - 1009
