1.1: tetrahydrofuran / 2 h / 20 °C / |Inert atmosphere 2.1: sodium hydroxide / ethanol / 3 h / |Inert atmosphere 2.2: |Inert atmosphere 3.1: hydrogen; bis(1,5-cyclooctadiene)-rhodium(I) tetrafluoroborate; tris (α-naphthyl)phosphine; (3aR,8aR)-(−)-(2,2-dimethyl-4,4,8,8-tetraphenyl-tetrahydro-[1,3]dioxolo[4,5-e][1,3,2]dioxaphosphepin-6-yl)dimethylamine / isopropyl alcohol / 20 h / 30 °C / 18751.9 Torr / |Inert atmosphere View Scheme

1.1: sulfuric acid; hydrogen bromide / water / 20 °C / |Inert atmosphere 2.1: sodium azide / water; acetone / 0.5 h / 20 °C / |Inert atmosphere 3.1: water; triphenylphosphine / tetrahydrofuran / 20 °C / |Inert atmosphere 4.1: tetrahydrofuran / 2 h / 20 °C / |Inert atmosphere 5.1: sodium hydroxide / ethanol / 3 h / |Inert atmosphere 5.2: |Inert atmosphere 6.1: hydrogen; bis(1,5-cyclooctadiene)-rhodium(I) tetrafluoroborate; tris (α-naphthyl)phosphine; (3aR,8aR)-(−)-(2,2-dimethyl-4,4,8,8-tetraphenyl-tetrahydro-[1,3]dioxolo[4,5-e][1,3,2]dioxaphosphepin-6-yl)dimethylamine / isopropyl alcohol / 20 h / 30 °C / 18751.9 Torr / |Inert atmosphere View Scheme

1.1: sodium azide / water; acetone / 0.5 h / 20 °C / |Inert atmosphere 2.1: water; triphenylphosphine / tetrahydrofuran / 20 °C / |Inert atmosphere 3.1: tetrahydrofuran / 2 h / 20 °C / |Inert atmosphere 4.1: sodium hydroxide / ethanol / 3 h / |Inert atmosphere 4.2: |Inert atmosphere 5.1: hydrogen; bis(1,5-cyclooctadiene)-rhodium(I) tetrafluoroborate; tris (α-naphthyl)phosphine; (3aR,8aR)-(−)-(2,2-dimethyl-4,4,8,8-tetraphenyl-tetrahydro-[1,3]dioxolo[4,5-e][1,3,2]dioxaphosphepin-6-yl)dimethylamine / isopropyl alcohol / 20 h / 30 °C / 18751.9 Torr / |Inert atmosphere View Scheme

1.1: water; triphenylphosphine / tetrahydrofuran / 20 °C / |Inert atmosphere 2.1: tetrahydrofuran / 2 h / 20 °C / |Inert atmosphere 3.1: sodium hydroxide / ethanol / 3 h / |Inert atmosphere 3.2: |Inert atmosphere 4.1: hydrogen; bis(1,5-cyclooctadiene)-rhodium(I) tetrafluoroborate; tris (α-naphthyl)phosphine; (3aR,8aR)-(−)-(2,2-dimethyl-4,4,8,8-tetraphenyl-tetrahydro-[1,3]dioxolo[4,5-e][1,3,2]dioxaphosphepin-6-yl)dimethylamine / isopropyl alcohol / 20 h / 30 °C / 18751.9 Torr / |Inert atmosphere View Scheme

1.1: sodium hydroxide / ethanol / 3 h / |Inert atmosphere 1.2: |Inert atmosphere 2.1: hydrogen; bis(1,5-cyclooctadiene)-rhodium(I) tetrafluoroborate; tris (α-naphthyl)phosphine; (3aR,8aR)-(−)-(2,2-dimethyl-4,4,8,8-tetraphenyl-tetrahydro-[1,3]dioxolo[4,5-e][1,3,2]dioxaphosphepin-6-yl)dimethylamine / isopropyl alcohol / 20 h / 30 °C / 18751.9 Torr / |Inert atmosphere View Scheme

1.1: 1,4-diaza-bicyclo[2.2.2]octane / 1,4-dioxane; water / 20 °C / |Inert atmosphere 2.1: sulfuric acid; hydrogen bromide / water / 20 °C / |Inert atmosphere 3.1: sodium azide / water; acetone / 0.5 h / 20 °C / |Inert atmosphere 4.1: water; triphenylphosphine / tetrahydrofuran / 20 °C / |Inert atmosphere 5.1: tetrahydrofuran / 2 h / 20 °C / |Inert atmosphere 6.1: sodium hydroxide / ethanol / 3 h / |Inert atmosphere 6.2: |Inert atmosphere 7.1: hydrogen; bis(1,5-cyclooctadiene)-rhodium(I) tetrafluoroborate; tris (α-naphthyl)phosphine; (3aR,8aR)-(−)-(2,2-dimethyl-4,4,8,8-tetraphenyl-tetrahydro-[1,3]dioxolo[4,5-e][1,3,2]dioxaphosphepin-6-yl)dimethylamine / isopropyl alcohol / 20 h / 30 °C / 18751.9 Torr / |Inert atmosphere View Scheme

1: 9-epi-QDU / water; toluene / 24 h / 20 °C 2: ammonium formate; palladium 10 on activated carbon / #tert!-butyl alcohol / 2 h / 60 °C View Scheme