5-(6-氨基嘌呤-9-基)-4-氯-2-(羟基甲基)四氢呋喃-3-醇合成路线 (共 3 条)
反应条件
tetrabutyl ammonium fluoride in tetrahydrofuran 0.166667 h; Ambient temperature;
参考文献
Fukukawa; Uedao; Hirano
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 5 p. 1582 - 1592
反应条件
1: 79 percent / triethylamine, DMAP / CH2Cl2 / 0.5 h / Ambient temperature 2: 63 percent / LiCl / hexamethylphosphoric acid triamide / 5 h / Ambient temperature 3: 82 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 0.17 h / Ambient temperature View Scheme
参考文献
Fukukawa; Uedao; Hirano
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 5 p. 1582 - 1592
反应条件
1: 63 percent / LiCl / hexamethylphosphoric acid triamide / 5 h / Ambient temperature 2: 82 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 0.17 h / Ambient temperature View Scheme
参考文献
Fukukawa; Uedao; Hirano
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 5 p. 1582 - 1592