(S)-(-)- α-甲基苄胺合成路线 （共 369 条）
反应条件
sodium tetrahydroborate; (S)-valinol; zirconium tetrachloride in tetrahydrofuran 48 h; Ambient temperature; Title compound not separated from byproducts;
参考文献
Itsuno, Shinichi; Sakurai, Yoshiki; Shimizu, Koji; Ito, Koichi
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1990 , # 7 p. 1859 - 1863
参考文献
Chapman, Daniel T.; Crout, David H. G.; Mahmoudian, Mahmoud; Scopes, David I. C.; Smith, Paul W.
Chemical Communications, 1996 , # 21 p. 2415 - 2416
反应条件
glutaryl-7-aminocephalosporanic acid acylase in water T=25°C; pH=7.0; Title compound not separated from byproducts;
参考文献
Raimondi, Stefano; Monti, Daniela; Pagnoni, Ugo Maria; Riva, Sergio
Advanced Synthesis and Catalysis, 2003 , vol. 345, # 6-7 p. 783 - 789
反应条件
1: 96 percent / ethanol / 0.75 h / Heating 2: KOH / methanol; H2O / 44 h / Heating View Scheme
参考文献
Schonenberger; Brossi
Helvetica Chimica Acta, 1986 , vol. 69, # 6 p. 1486 - 1497
反应条件
1: tert-butyl hypochlorite / diethyl ether / 0.5 h / 0 °C 2: sodium ethoxide / ethanol / 1 h / 40 °C 3: 5percent sulfuric acid / H2O / 2 h / Ambient temperature View Scheme
参考文献
Ikota; Achiwa; Yamada
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 3 p. 887 - 894
反应条件
1: tert-butyl hypochlorite / diethyl ether / 0.5 h / 0 °C 2: sodium ethoxide / ethanol / 1 h / 40 °C 3: 5percent sulfuric acid / H2O / 2 h / Ambient temperature View Scheme
参考文献
Ikota; Achiwa; Yamada
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 3 p. 887 - 894
反应条件
1: sodium ethoxide / ethanol / 1 h / 40 °C 2: 5percent sulfuric acid / H2O / 2 h / Ambient temperature View Scheme
参考文献
Ikota; Achiwa; Yamada
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 3 p. 887 - 894
反应条件
1: tert-butyl hypochlorite / diethyl ether / 0.5 h / 0 °C 2: sodium ethoxide / ethanol / 1 h / 40 °C 3: 5percent sulfuric acid / H2O / 2 h / Ambient temperature View Scheme
参考文献
Ikota; Achiwa; Yamada
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 3 p. 887 - 894
反应条件
1: sodium ethoxide / ethanol / 1 h / 40 °C 2: 5percent sulfuric acid / H2O / 2 h / Ambient temperature View Scheme
参考文献
Ikota; Achiwa; Yamada
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 3 p. 887 - 894
反应条件
1: sodium ethoxide / ethanol / 1 h / 40 °C 2: 5percent sulfuric acid / H2O / 2 h / Ambient temperature View Scheme
参考文献
Ikota; Achiwa; Yamada
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 3 p. 887 - 894
