(S)-(-)- α-甲基苄胺合成路线 （共 369 条）
反应条件
1: recombinant ω-transaminase from Burkholderia vietnamiensis G4; pyridoxal 5'-phosphate / aq. buffer / 12 h / 37 °C / pH 7.4 / |Resolution of racemate; |Enzymatic reaction 2: recombinant ω-transaminase from Burkholderia vietnamiensis G4; pyridoxal 5'-phosphate / aq. phosphate buffer / 0.08 h / 37 °C / pH 7.4 / |Enzymatic reaction 3: recombinant ω-transaminase from Burkholderia vietnamiensis G4; pyridoxal 5'-phosphate / aq. phosphate buffer / 12 h / 37 °C / pH 7.4 / |Enzymatic reaction View Scheme
参考文献
Jiang, Jinju; Chen, Xi; Feng, Jinhui; Wu, Qiaqing; Zhu, Dunming
Journal of Molecular Catalysis B: Enzymatic, 2014 , vol. 100, p. 32 - 39
反应条件
1: recombinant ω-transaminase from Burkholderia vietnamiensis G4; pyridoxal 5'-phosphate / aq. phosphate buffer / 0.08 h / 37 °C / pH 7.4 / |Enzymatic reaction 2: recombinant ω-transaminase from Burkholderia vietnamiensis G4; pyridoxal 5'-phosphate / aq. phosphate buffer / 12 h / 37 °C / pH 7.4 / |Enzymatic reaction View Scheme
参考文献
Jiang, Jinju; Chen, Xi; Feng, Jinhui; Wu, Qiaqing; Zhu, Dunming
Journal of Molecular Catalysis B: Enzymatic, 2014 , vol. 100, p. 32 - 39
反应条件
hydrogenchloride; periodic acid; methylamine 1) aq. MeOH, RT, 3h, 2) ether, 30 min; Yield given. Multistep reaction;
参考文献
Chang, Zen-Yu; Coates, Robert M.
Journal of Organic Chemistry, 1990 , vol. 55, # 11 p. 3475 - 3483
反应条件
in dimethyl sulfoxide T=25°C; Equilibrium constant;
参考文献
Zingg, S. P.; Arnett, Edward M.; McPhail, Andrew T.; Bothner-By, Aksel A.; Gilkerson, W. R.
Journal of the American Chemical Society, 1988 , vol. 110, # 5 p. 1565 - 1580
反应条件
in dimethyl sulfoxide T=25°C; Equilibrium constant;
参考文献
Zingg, S. P.; Arnett, Edward M.; McPhail, Andrew T.; Bothner-By, Aksel A.; Gilkerson, W. R.
Journal of the American Chemical Society, 1988 , vol. 110, # 5 p. 1565 - 1580
反应条件
sulfuric acid in water 2 h; Ambient temperature; Yield given;
参考文献
Ikota; Achiwa; Yamada
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 3 p. 887 - 894
反应条件
sulfuric acid in water 2 h; Ambient temperature; Yield given;
参考文献
Ikota; Achiwa; Yamada
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 3 p. 887 - 894
反应条件
sulfuric acid in water 2 h; Ambient temperature; Yield given;
参考文献
Ikota; Achiwa; Yamada
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 3 p. 887 - 894
反应条件
sulfuric acid in water 2 h; Ambient temperature; Yield given;
参考文献
Ikota; Achiwa; Yamada
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 3 p. 887 - 894
反应条件
sulfuric acid in water 2 h; Ambient temperature; Yield given;
参考文献
Ikota; Achiwa; Yamada
Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 3 p. 887 - 894
