(S)-(-)- α-甲基苄胺合成路线 （共 369 条）
反应条件
(1S,2R)-cis-2-aminocyclopentanol; borane in tetrahydrofuran 40 h; Ambient temperatureother chiral ligands, enantioselectivity; Product distribution;
参考文献
Didier, Eric; Loubinoux, Bernard; Ramos Tombo, Gerardo H.; Rihs, Grety
Tetrahedron, 1991 , vol. 47, # 27 p. 4941 - 4958
反应条件
anschliessend Erwaermen mit Brom;
参考文献
Arcus; Kenyon
Journal of the Chemical Society, 1939 , p. 916,920
反应条件
pyridoxal 5'-phosphate; recombinant ω-transaminase from Burkholderia vietnamiensis G4 in aq. phosphate buffer T=37°C; pH=7.4; 0.0833333 h; Enzymatic reaction;
参考文献
Journal of Molecular Catalysis B: Enzymatic, , vol. 100, p. 32 - 39
反应条件
pyridoxal 5'-phosphate; recombinant ω-transaminase from Burkholderia vietnamiensis G4 in aq. phosphate buffer T=37°C; pH=7.4; 0.0833333 h; Enzymatic reaction; enantioselective reaction;
参考文献
Jiang, Jinju; Chen, Xi; Feng, Jinhui; Wu, Qiaqing; Zhu, Dunming
Journal of Molecular Catalysis B: Enzymatic, 2014 , vol. 100, p. 32 - 39
反应条件
Novozymereg;435; hydrogen in toluene T=70°C; 35 h; Enzymatic reaction; chemoselective reaction;
参考文献
Shi, Jing; Li, Xiang; Wang, Quanrui; Zhang, Yahong; Tang, Yi
Journal of Catalysis, 2012 , vol. 291, p. 87 - 94
反应条件
immobilized lipase B from Candida antarctica (CAL-B, Novozyme 435) in toluene T=110°C; 1 h; Inert atmosphereResolution of racemate;
参考文献
Geukens, Inge; Plessers, Eva; Seo, Jin Won; De Vos, Dirk E.
European Journal of Inorganic Chemistry, 2013 , # 14 p. 2623 - 2628
反应条件
immobilized lipase B from Candida antarctica (CAL-B, Novozyme 435) in toluene T=110°C; 1 h; Inert atmosphereResolution of racemate;
参考文献
Geukens, Inge; Plessers, Eva; Seo, Jin Won; De Vos, Dirk E.
European Journal of Inorganic Chemistry, 2013 , # 14 p. 2623 - 2628
反应条件
1: H2 / Pd/BaCO3 / toluene / 72 h / 70 °C / 1500.15 Torr 2: H2 / Pd/CaCO3; Candida Antarctica lipase B / toluene / 24 h / 70 °C / 75.01 Torr View Scheme
参考文献
Parvulescu, Andrei N.; Jacobs, Pierre A.; De Vos, Dirk E.
Chemistry - A European Journal, 2007 , vol. 13, # 7 p. 2034 - 2043
反应条件
pyridoxal 5'-phosphate; recombinant ω-transaminase from Burkholderia vietnamiensis G4 in aq. phosphate buffer T=37°C; pH=7.4; 0.0833333 h; Enzymatic reaction; enantioselective reaction;
参考文献
Jiang, Jinju; Chen, Xi; Feng, Jinhui; Wu, Qiaqing; Zhu, Dunming
Journal of Molecular Catalysis B: Enzymatic, 2014 , vol. 100, p. 32 - 39
参考文献
Pettersson
Arkiv foer Kemi, 1956 , vol. 10, p. 297,299, 302
