(S)-(-)- α-甲基苄胺合成路线 （共 369 条）
反应条件
pyridoxal 5'-phosphate; recombinant ω-transaminase from Burkholderia vietnamiensis G4 in aq. phosphate buffer T=37°C; pH=7.4; 0.0833333 h; Enzymatic reaction; enantioselective reaction;
参考文献
Jiang, Jinju; Chen, Xi; Feng, Jinhui; Wu, Qiaqing; Zhu, Dunming
Journal of Molecular Catalysis B: Enzymatic, 2014 , vol. 100, p. 32 - 39
反应条件
sodium carbonate in diethyl ether T=0 - 5°C; 1 h;
参考文献
Takaba, Keiko
Heterocycles, 1997 , vol. 45, # 6 p. 1111 - 1119
反应条件
TEA in dichloromethane T=20°C; 16 h;
参考文献
Galbo, Fabrizio Lo; Occhiato, Ernesto G.; Guarna, Antonio; Faggi, Cristina
Journal of Organic Chemistry, 2003 , vol. 68, # 16 p. 6360 - 6368
反应条件
Ni T=110°C; 1 h; Inert atmosphere; Reagent/catalyst;
参考文献
Geukens, Inge; Plessers, Eva; Seo, Jin Won; De Vos, Dirk E.
European Journal of Inorganic Chemistry, 2013 , # 14 p. 2623 - 2628
反应条件
hydrogen; Pd-BaSO4 in toluene T=70°C; P=75.0075 Torr; 24 h; Kinetics; Further Variations:Catalysts;
参考文献
Parvulescu, Andrei N.; Jacobs, Pierre A.; De Vos, Dirk E.
Chemistry - A European Journal, 2007 , vol. 13, # 7 p. 2034 - 2043
反应条件
BM-ωTA; ωTA ATA-117 102907WW; pyridoxal 5'-phosphate T=30°C; pH=7; 24 h; aq. phosphate buffer;
参考文献
Koszelewski, Dominik; Grischek, Barbara; Glueck, Silvia M.; Kroutil, Wolfgang; Faber, Kurt
Chemistry - A European Journal, 2011 , vol. 17, # 1 p. 378 - 383
反应条件
Rodionov reaction; microwave irradiation;
参考文献
Russian Journal of Organic Chemistry, , vol. 39, # 5 p. 692 - 697
反应条件
formic acid; resin (p-trityl-O-NH2); benzotriazol-1-ol; dicyclohexyl-carbodiimide 1.) THF, 60 deg C, 6 h; 2.) DMF rt.; 3.) THF 1 h;; Yield given. Multistep reaction;
参考文献
Tetrahedron Letters, , vol. 38, # 41 p. 7233 - 7236
反应条件
1: 41 percent / t-BuOK / tetrahydrofuran / 52 h / Heating 2: KNO2, 18-crown-6 View Scheme
参考文献
Heggvik, Lindis R.; Fiksdahl, Anne
Tetrahedron Asymmetry, 1997 , vol. 8, # 13 p. 2189 - 2192
反应条件
water; acetic acid; sodium nitrite 1.) RT, 18 h, 2.) 1 h; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Ileby, Nina; Kuzma, Marek; Heggvik, Lindis R.; Sorbye, Karsten; Fiksdahl, Anne
Tetrahedron Asymmetry, 1997 , vol. 8, # 13 p. 2193 - 2198
