(S)-(-)- α-甲基苄胺合成路线 （共 369 条）
反应条件
in xylene retro-Diels-Alder reaction; 12 h; Heating;
参考文献
Chihab-Eddine, Abderrahim; Dach, Adam; Jilale, Abderrahim; Decroix, Bernard
Tetrahedron Letters, 2001 , vol. 42, # 4 p. 573 - 576
反应条件
1: CH2Cl2 / 16 h / 0 - 20 °C 2: (COCl)2 / dimethylformamide / 8 h / 20 °C 3: NEt3 / CH2Cl2 / 1 h / 20 °C View Scheme
参考文献
Tokioka, Kyohei; Masuda, Satoshi; Fujii, Tomomi; Hata, Yasuo; Yamamoto, Yukio
Tetrahedron Asymmetry, 1997 , vol. 8, # 1 p. 101 - 107
参考文献
Uhan Corporation
Patent: US5990311 A1, 1999 ;
反应条件
in dimethyl sulfoxide T=50°C; 72 h;
参考文献
Couty, Francois; Evano, Gwilherm; Vargas-Sanchez, Monica; Bouzas, Gloria
Journal of Organic Chemistry, 2005 , vol. 70, # 22 p. 9028 - 9031
反应条件
in water 0.333333 h; Sonication;
参考文献
Aparicio, David M.; Teran, Joel L.; Roa, Luis F.; Gnecco, Dino; Juarez, Jorge R.; Orea, Maria L.; Mendoza, Angel; Flores-Alamo, Marcos; Micouin, Laurent
Synthesis, 2011 , # 14 art. no. M11511SS, p. 2310 - 2320
反应条件
1: 100 percent / pyridine / CH2Cl2 / 0.5 h / 0 °C 2: 81 percent / LAH / tetrahydrofuran / 64 h View Scheme
参考文献
Nelson, Todd D.; Rosen, Jonathan D.; Brands, Karel M.J.; Craig, Bridgette; Huffman, Mark A.; McNamara, James M.
Tetrahedron Letters, 2004 , vol. 45, # 48 p. 8917 - 8920
参考文献
Chan; Laughton; Queener; Stevens
Journal of Medicinal Chemistry, 2001 , vol. 44, # 16 p. 2555 - 2564
反应条件
BM-ωTA; ωTA ATA-117 102907WW; pyridoxal 5'-phosphate T=30°C; pH=7; 24 h; aq. phosphate buffer;
参考文献
Koszelewski, Dominik; Grischek, Barbara; Glueck, Silvia M.; Kroutil, Wolfgang; Faber, Kurt
Chemistry - A European Journal, 2011 , vol. 17, # 1 p. 378 - 383
反应条件
1: CH2Cl2 / 1.25 h / 20 °C / cooling 2: 36.5 g / I2; PhI(OCOCF3)2 / 20 °C / cooling 3: NaOH / methanol; H2O / 2.5 h / 20 °C View Scheme
参考文献
Tagat; Steensma; McCombie; Nazareno; Lin; Neustadt; Cox; Xu; Wojcik; Murray; Vantuno; Baroudy; Strizki
Journal of Medicinal Chemistry, 2001 , vol. 44, # 21 p. 3343 - 3346
反应条件
hydrogen bromide in dichloromethane; ethyl acetate
参考文献
Uhan Corporation
Patent: US5990311 A1, 1999 ;
