(S)-(-)- α-甲基苄胺合成路线 （共 369 条）
参考文献
Mandoli, Alessandro; Arnold, Leggy A.; De Vries, Andre H.M.; Salvadori, Piero; Feringa, Ben L.
Tetrahedron Asymmetry, 2001 , vol. 12, # 13 p. 1929 - 1937
反应条件
in methanol 96 h; Heating;
参考文献
Estermann, Heinrich; Seebach, Dieter
Helvetica Chimica Acta, 1988 , vol. 71, p. 1824 - 1840
反应条件
pyridoxal 5'-phosphate; recombinant ω-transaminase from Burkholderia vietnamiensis G4 in aq. phosphate buffer T=37°C; pH=7.4; 0.0833333 h; Enzymatic reaction;
参考文献
Jiang, Jinju; Chen, Xi; Feng, Jinhui; Wu, Qiaqing; Zhu, Dunming
Journal of Molecular Catalysis B: Enzymatic, 2014 , vol. 100, p. 32 - 39
反应条件
1: 25 percent / 4A sieves / toluene / Ambient temperature 2: 51 percent / LiAlH / tetrahydrofuran / 24 h / Heating View Scheme
参考文献
Culbertson, Townley P.; Domagala, John M.; Nichols, Jeffery B.; Priebe, Stephen; Skeean, Richard W.
Journal of Medicinal Chemistry, 1987 , vol. 30, # 10 p. 1711 - 1715
反应条件
1,4-dioxo-1,2,3,4-tetrahydro-phthalazine T=80 - 95°C; 40 h;
参考文献
Iwata, Masaaki; Kuzuhara, Hiroyoshi
Chemistry Letters, 1989 , p. 2029 - 2030
反应条件
carbon in ethyl acetate Heating;
参考文献
Journal of Medicinal Chemistry, , vol. 39, # 5 p. 1157 - 1163
反应条件
hydrogenchloride in toluene
参考文献
Australian Journal of Chemistry, , vol. 31, p. 1965 - 1980
反应条件
pyridoxal 5'-phosphate; recombinant ω-transaminase from Burkholderia vietnamiensis G4 in aq. phosphate buffer T=37°C; pH=7.4; 0.0833333 h; Enzymatic reaction;
参考文献
Jiang, Jinju; Chen, Xi; Feng, Jinhui; Wu, Qiaqing; Zhu, Dunming
Journal of Molecular Catalysis B: Enzymatic, 2014 , vol. 100, p. 32 - 39
反应条件
sodium tetrahydroborate in methanol 1.) RT, 2 h; 2.) 20-28 deg C, 1 h; 3.) RT, 16 h;
参考文献
Qun, Li; Chu, Daniel T. W.; Raye, Kathleen; Claiborne, Akiyo; Seif, Louis; Macri, Bryan; Plattner, Jacob J.
Tetrahedron Letters, 1995 , vol. 36, # 46 p. 8391 - 8394
反应条件
1: benzyl alcohol With 2,2,6,6-tetramethyl-piperidine-N-oxyl; [bis(acetoxy)iodo]benzene in dichloromethane T=20°C; 16 h; 2: (S)-1-phenyl-ethylamine With sodium tris(acetoxy)borohydride in dichloromethane optical yield given as percent eechemoselective reaction;
参考文献
Guerin, Claire; Bellosta, Veronique; Guillamot, Gerard; Cossy, Janine
Organic Letters, 2011 , vol. 13, # 13 p. 3534 - 3537
