2-氯-5-[(三甲基硅烷基)乙炔基]吡啶合成路线 （共 4 条）
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; triethylamine T=20°C; Condensation; Stille cross-coupling; 48 h;
参考文献
Baxter
Journal of Organic Chemistry, 2001 , vol. 66, # 12 p. 4170 - 4179
反应条件
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide in triethylamine T=20°C;
参考文献
Bunzen, Jens; Kiehne, Ulf; Benkhaeuser-Schunk, Christian; Luetzen, Arne
Organic Letters, 2009 , vol. 11, # 21 p. 4786 - 4789
反应条件
sodium hydroxide in tetrahydrofuran; methanol T=20°C; Hydrolysis; 24 h;
参考文献
Baxter
Journal of Organic Chemistry, 2001 , vol. 66, # 12 p. 4170 - 4179
反应条件
1: 95 percent / aq. NaOH / methanol; tetrahydrofuran / 24 h / 20 °C
2: Pd(PPh3)2Cl2; CuI / triethylamine
View Scheme
参考文献
Baxter
Journal of Organic Chemistry, 2000 , vol. 65, # 5 p. 1257 - 1272
