3-甲基吲哚-2-甲酸乙酯合成路线 （共 26 条）
反应条件
1: AcOH / 0.5 h / 60 °C 2: HCl / dioxane / 6 h / 110 °C View Scheme
参考文献
Liu, Kevin G.; Robichaud, Albert J.; Lo, Jennifer R.; Mattes, James F.; Cai, Yanxuan
Organic Letters, 2006 , vol. 8, # 25 p. 5769 - 5771
反应条件
1: AcOH / 0.5 h / 60 °C 2: HCl / dioxane / 6 h / 110 °C View Scheme
参考文献
Liu, Kevin G.; Robichaud, Albert J.; Lo, Jennifer R.; Mattes, James F.; Cai, Yanxuan
Organic Letters, 2006 , vol. 8, # 25 p. 5769 - 5771
反应条件
1: Rh2(OAc)4 / toluene / 80 °C 2: DBU / toluene / 20 °C View Scheme
参考文献
Nakamura, Yoshinori; Ukita, Tatsuzo
Organic Letters, 2002 , vol. 4, # 14 p. 2317 - 2320
反应条件
1: 1.) NaN3, conc. H2SO4, 2.) SOCl2, Et3N / 1.) DMSO, 90 deg C, 2 h, 2.) CH2Cl2, RT, 4 h 2: 74 percent / xylene / 0.83 h / Heating View Scheme
参考文献
Murakami, Yasuoki; Watanabe, Toshiko; Suzuki, Hideharu; Kotake, Nobuyo; Takahashi, Tomoko; Toyonari, Kiyono; Ohno, Masami; Takase, Kyoko; Suzuki, Takayuki; Kondo, Kazuhiro
Chemical and Pharmaceutical Bulletin, 1997 , vol. 45, # 11 p. 1739 - 1744
反应条件
1: 96 percent / benzene / 7 h / Heating 2: 40 percent / triethyl phosphite / 3 h / 170 °C View Scheme
参考文献
Mali; Yadav
Synthesis, 1984 , vol. NO. 10, p. 862 - 865
反应条件
1.1: NaNO2; 35 percent aq. HCl 1.2: 50 percent aq.KOH / ethanol / 0.5 h / 0 °C 2.1: 10 percent HCl / ethanol / 0.25 h / Heating View Scheme
参考文献
Kitano, Masafumi; Kojima, Atsuyuki; Nakano, Kazuhiro; Miyagishi, Akira; Noguchi, Tsuyoshi; Ohashi, Naohito
Chemical and Pharmaceutical Bulletin, 1999 , vol. 47, # 11 p. 1538 - 1548
反应条件
1: 24 h / 70 °C 2: 1,5,7-triazabicyclo[4.4.0]dec-5-ene bound to polystyrene / acetonitrile / 5 h / 20 °C 3: tris-(dibenzylideneacetone)dipalladium(0); triethylamine; tris-(o-tolyl)phosphine / N,N-dimethyl-formamide / 12 h / 110 °C View Scheme
参考文献
Palmieri, Alessandro; Gabrielli, Serena; Maggi, Raimondo; Ballini, Roberto
Synlett, 2014 , vol. 25, # 1 art. no. ST-2013-D0913-L, p. 128 - 132
反应条件
1: 24 h / 70 °C 2: 1,5,7-triazabicyclo[4.4.0]dec-5-ene bound to polystyrene / acetonitrile / 5 h / 20 °C 3: tris-(dibenzylideneacetone)dipalladium(0); triethylamine; tris-(o-tolyl)phosphine / N,N-dimethyl-formamide / 12 h / 110 °C View Scheme
参考文献
Palmieri, Alessandro; Gabrielli, Serena; Maggi, Raimondo; Ballini, Roberto
Synlett, 2014 , vol. 25, # 1 art. no. ST-2013-D0913-L, p. 128 - 132
反应条件
ethanol; sulfuric acid
参考文献
Andrisano; Vitali
Gazzetta Chimica Italiana, 1957 , vol. 87, p. 949,953, 958
参考文献
Wislicenus; Arnold
Chemische Berichte, 1887 , vol. 20, p. 3395
Justus Liebigs Annalen der Chemie, 1888 , vol. 246, p. 334
