7-氯-1,4-二氢-6-硝基-4-氧代-3-喹啉甲腈合成路线 （共 6 条）
反应条件
in dowtherm A T=260°C; 2 h;
参考文献
Wyeth Holdings Corporation
Patent: EP1950201 A1, 2008 ;
Location in patent: Page/Page column 69 ;
EP 1950201 A1
反应条件
in N,N-dimethyl-formamide
参考文献
American Home Products Corporation
Patent: US2001/51620 A1, 2001 ;
US 20010051620 A1
反应条件
1.2: Dowtherm / Heating 2.1: aq. NaOH / Heating 3.1: CDI / dimethylformamide 3.2: NH3 4.1: cyanuric chloride View Scheme
参考文献
Berger, Dan; Dutia, Minu; Powell, Dennis; Wu, Biqi; Wissner, Allan; DeMorin, Frenel; Weber, Jennifer; Boschelli, Frank
Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 19 p. 2761 - 2765
反应条件
1.1: CDI / dimethylformamide 1.2: NH3 2.1: cyanuric chloride View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 12, # 19 p. 2761 - 2765
反应条件
1.1: aq. NaOH / Heating 2.1: CDI / dimethylformamide 2.2: NH3 3.1: cyanuric chloride View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 12, # 19 p. 2761 - 2765
反应条件
2,4,6-trichloro-1,3,5-triazine
参考文献
Berger, Dan; Dutia, Minu; Powell, Dennis; Wu, Biqi; Wissner, Allan; DeMorin, Frenel; Weber, Jennifer; Boschelli, Frank
Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 19 p. 2761 - 2765
