二乙基丙烷二亚氨酸酯二盐酸盐合成路线 （共 4 条）
反应条件
hydrogenchloride in benzene T=15°C;
参考文献
Fairley; Tidwell; Donkor; Naiman; Ohemeng; Lombardy; Bentley; Cory
Journal of Medicinal Chemistry, 1993 , vol. 36, # 12 p. 1746 - 1753
反应条件
potassium carbonate in diethyl ether T=-10°C;
参考文献
Krug, Barbara; Hartke, Klaus
Archiv der Pharmazie (Weinheim, Germany), 1984 , vol. 317, # 10 p. 883 - 890
反应条件
hydrazine in ethanol T=4°C; 16.1667 h;
参考文献
NOVARTIS AG
Patent: WO2009/106539 A1, 2009 ;
Location in patent: Page/Page column 31 ;
反应条件
potassium hydroxide; sodium hydrogencarbonate in methanol; water; acetonitrile
参考文献
Hoechst Aktiengesellschaft
Patent: US4960887 A1, 1990 ;
