alpha-溴-4-甲氧基苯乙酮合成路线 （共 261 条）
反应条件
2: 75 percent / ZnI2, NaCNBH4 / 1,2-dichloro-ethane / 6 h / Heating View Scheme
参考文献
Lau, Cheuk K.; Belanger, Patrice C.; Scheigetz, John; Dufresne, Claude; Williams, Haydn W. R.; et al.
Journal of Medicinal Chemistry, 1989 , vol. 32, # 6 p. 1190 - 1197
反应条件
1: 2-bromo-4'-methoxy-acetophenone With thiamine hydrochloride in ethanol T=20°C; 0.25 h; Green chemistry; 2: 2-Hydroxy-4-methoxy-benzaldehyde in ethanol T=20°C; 1.58333 h; Green chemistry;
参考文献
Mishra, Priya; Singh, Sarita; Ankit, Preyas; Fatma, Shahin; Singh, Divya; Singh, Jagdamba
Bulletin of the Korean Chemical Society, 2013 , vol. 34, # 4 p. 1070 - 1076
反应条件
in ethanol 1 h; Reflux;
参考文献
TAIVEX THERAPEUTICS CORPORATION; HUANG, Yu-Ling; CHUANG, Shih-Hsien; LEE, Ying-Shuan Eda; HUANG, Jiann-Jyh; LAU, Johnson
Patent: WO2013/82324 A1, 2013 ;
Location in patent: Paragraph 00350 ;
反应条件
aluminum oxide; ammonium acetate; silica gel in benzene T=90°C; 16 h;
参考文献
Jung, Kwan-Young; Kim, Soo-Kyung; Gao, Zhan-Guo; Gross, Ariel S.; Melman, Neli; Jacobson, Kenneth A.; Kim, Yong-Chul
Bioorganic and Medicinal Chemistry, 2004 , vol. 12, # 3 p. 613 - 623
反应条件
1-methyl-1H-imidazole in water; isopropyl alcohol T=20°C; 1.5 h;
参考文献
Meshram; Thakur, Pramod B.; Madhu Babu; Bangade, Vikas M.
Tetrahedron Letters, 2012 , vol. 53, # 39 p. 5265 - 5269
反应条件
Yield given. Multistep reaction;
参考文献
Kearney; Fernandez; Flygare
Journal of Organic Chemistry, 1998 , vol. 63, # 1 p. 196 - 200
反应条件
1: in ethanol T=78°C; 16 h; 2: With sodium hydroxide in dichloromethane; water
参考文献
Aginagalde, Maialen; Vara, Yosu; Arrieta, Ana; Zangi, Ronen; Cebolla, Vicente L.; Delgado-Camon, Arantzazu; Cossio, Fernando P.
Journal of Organic Chemistry, 2010 , vol. 75, # 9 p. 2776 - 2784
反应条件
1: 89 percent / acetone / 20 °C 2: 83 percent / 2,6-lutidine; dilauroyl peroxide / cyclohexane / Heating 3: 92 percent / Bu3SnH; AIBN / toluene / 2.5 h / Heating 4: 57 percent / oxalic acid; silica gel 5: 93 percent / AcOH; AcONH4; air / 1.5 h / Heating View Scheme
参考文献
Boivin, Jean; Carpentier, Floriane; Jrad, Rafik
Synthesis, 2006 , # 10 p. 1664 - 1672
参考文献
Dainippon Sumitomo Pharma Co., Ltd.
Patent: EP1647546 A1, 2006 ;
Location in patent: Page/Page column 35 ;
反应条件
1: water 2: copper (II)-acetate; aqueous NH3 View Scheme
参考文献
Weidenhagen; Herrmann
Chemische Berichte, 1935 , vol. 68, p. 1953,1956
