alpha-溴-4-甲氧基苯乙酮合成路线 （共 261 条）
反应条件
potassium phosphate Rap-Stoermer reaction; 0.0333333 h; microwave irradiation;
参考文献
Rao, Maddali L.N.; Awasthi, Dheeraj K.; Banerjee, Debasis
Tetrahedron Letters, 2007 , vol. 48, # 3 p. 431 - 434
反应条件
1: in ethanol 2 h; Heating / reflux; 2: With sodium hydrogencarbonate in ethanol 15 h; Heating / reflux;
参考文献
AUSTRALIAN NUCLEAR SCIENCE and TECHNOLOGY ORGANISATION
Patent: WO2008/22396 A1, 2008 ;
Location in patent: Page/Page column 44 ;
反应条件
T=20°C; 0.166667 h; grindingneat (no solvent);
参考文献
Zhu, Dongjian; Chen, Jiuxi; Wu, Dengze; Liu, Miaochang; Ding, Jinchang; Wu, Huayue
Journal of Chemical Research, 2009 , # 2 p. 84 - 86
反应条件
1: acetone / |Reflux 2: hydrogenchloride / water / 1 h / |Reflux View Scheme
参考文献
Kamal, Ahmed; Reddy, Vangala Santhosh; Karnewar, Santosh; Chourasiya, Sumit S.; Shaik, Anver Basha; Kumar, G. Bharath; Kishor, Chandan; Reddy, M. Kashi; Narasimha Rao; Nagabhushana, Ananthamurthy; Ramakrishna, Kallaganti V. S.; Addlagatta, Anthony; Kotamraju, Srigiridhar
ChemMedChem, 2013 , vol. 8, # 12 p. 2015 - 2025
反应条件
1: 0.02 h / 100 °C / Microwave irradiation; Neat (no solvent) 2: urea / 150 °C / Microwave irradiation; Neat (no solvent) View Scheme
参考文献
Motevalli, Kourosh; Yaghoubi, Zahra; Mirzazadeh, Roghieh
E-Journal of Chemistry, 2012 , vol. 9, # 3 p. 1047 - 1052
参考文献
Montedison S.p.A.
Patent: US4328356 A1, 1982 ;
反应条件
1: p-TsOH / methanol / 1 h 2: AgBF4 / methanol / 25 °C / reaction order and rate constants for the reaction between methyl acetals of primary α-halogenoakyl aryl ketones and AgBF4; reaction with AgNO3; effect of the substituent in aromatic ring 3: 92 percent / aq. NaOH / methanol / 4 h / Ambient temperature View Scheme
参考文献
Castaldi, Graziano; Giordano, Claudio; Uggeri, Fulvio
Synthesis, 1985 , # 5 p. 505 - 506
反应条件
1: sodium azide; potassium iodide / water; acetonitrile / 1 h / 60 °C / |Green chemistry 2: sodium tetrahydroborate / methanol / 1.25 h / 5 - 20 °C / |Green chemistry 3: hydrogen; palladium 10 on activated carbon / methanol / 2 h / 30 °C / 7500.75 Torr / |Green chemistry 4: sodium hydroxide / water; tert-butyl methyl ether / 1 h / 20 °C / |Green chemistry View Scheme
参考文献
Schrittwieser, Joerg H.; Coccia, Francesca; Kara, Selin; Grischek, Barbara; Kroutil, Wolfgang; D'Alessandro, Nicola; Hollmann, Frank
Green Chemistry, 2013 , vol. 15, # 12 p. 3318 - 3331
反应条件
aluminium trichloride in dichloromethane T=0°C; 1 h;
参考文献
Dehmel, Florian; Ciossek, Thomas; Maier, Thomas; Weinbrenner, Steffen; Schmidt, Beate; Zoche, Martin; Beckers, Thomas
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 17 p. 4746 - 4752
反应条件
1: ethyl 2-amidinoacetate hydrochloride With sodium ethanolate in ethanol T=0 - 20°C; Inert atmosphere; 2: 2-bromo-4'-methoxy-acetophenone in ethanol T=20 - 60°C; Inert atmosphere;
参考文献
Sorum, Christopher; Simic, Nebojsa; Sundby, Eirik; Hoff, Bard Helge
Magnetic Resonance in Chemistry, 2010 , vol. 48, # 3 p. 244 - 248
