alpha-溴-4-甲氧基苯乙酮合成路线 （共 261 条）
反应条件
in chloroform
T=20°C; Delepine reaction; 12 h;
参考文献
Loughlin, Wendy A.; Henderson, Luke C.; Elson, Kathryn E.; Murphy, Michelle E.
Synthesis, 2006 , # 12 p. 1975 - 1980
反应条件
sodium azide in dimethyl sulfoxide
0.116667 h; Ambient temperature;
参考文献
Schrittwieser, Joerg H.; Coccia, Francesca; Kara, Selin; Grischek, Barbara; Kroutil, Wolfgang; D'Alessandro, Nicola; Hollmann, Frank
Green Chemistry, 2013 , vol. 15, # 12 p. 3318 - 3331
反应条件
1: N2H4*H2O
2: MnO2
View Scheme
参考文献
Hauptmann,S.; Wilde,H.
Journal fuer Praktische Chemie (Leipzig), 1969 , vol. 311, p. 604 - 613
反应条件
1: acetone
2: ethanol / Heating
3: aq. H2SO4
View Scheme
参考文献
Ding, Huaiwei; Chen, Zhe; Zhang, Cunlong; Xin, Tian; Wang, Yini; Song, Hongrui; Jiang, Yuyang; Chen, Yuzong; Xu, Yongnan; Tan, Chunyan
Molecules, 2012 , vol. 17, # 4 p. 4703 - 4716
反应条件
1: 90 percent / NaOEt / ethanol; acetonitrile / 2 h / Ambient temperature
2: 86.8 percent / NaIO4 / H2O; methanol / 24 h / Ambient temperature
3: 47.3 percent / (CF3CO)2O / CH2Cl2 / Ambient temperature
View Scheme
参考文献
Kataoka, Tadashi; Tomoto, Akihiko; Shimizu, Hiroshi; Hori, Mikio
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 12 p. 2913 - 2920
反应条件
potassium iodide in acetone
参考文献
BLASCHIM S.p.A.
Patent: EP34871 B2, 1993 ;
反应条件
tetrabutylammomium bromide; sodium iodide in water
T=20°C; 0.5 h;
参考文献
Sayyahi, Soheil; Saghanezhad, Jafar
Chinese Chemical Letters, 2011 , vol. 22, # 3 p. 300 - 302
反应条件
1: 80 percent / triethyl orthoformate, methanesulfonic acid / 2 h / 35 °C
2: 98 percent / anhydrous zinc bromide / toluene / 3 h / Heating
View Scheme
参考文献
Castaldi, Graziano; Belli, Aldo; Uggeri, Fulvio; Giordano, Claudio
Journal of Organic Chemistry, 1983 , vol. 48, # 24 p. 4658 - 4661
反应条件
in ethanol
6 h; Heating;
参考文献
Sawhney, S. N.; Kodali, Dharma R.; Dhindsa, G. S.; Singh, S. P.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1982 , vol. 21, # 2 p. 134 - 138
反应条件
1: 90 percent / DIEA / dimethylformamide / 4 h / 20 °C
2: 87 percent / pyridine / ethanol / 2 h / Heating
3: 80 percent / BH3*THF / tetrahydrofuran / 3.5 h / Heating
4: 75 percent / sodium cyanoborohydride; HCl / methanol / 24 h / 20 °C
5: HF; anisole / 1 h / 0 °C
6: 505 mg / NaOH / H2O; ethanol / 1 h / 20 °C
View Scheme
参考文献
Tchertchian, Sylvie; Hartley, Oliver; Botti, Paolo
Journal of Organic Chemistry, 2004 , vol. 69, # 26 p. 9208 - 9214
