alpha-溴-4-甲氧基苯乙酮合成路线 （共 261 条）
反应条件
in ethanol
1.5 h; Heating;
参考文献
Kelarev, V. I.; Shvekhgeimer, G. A.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1984 , vol. 20, # 6 p. 614 - 617
Khimiya Geterotsiklicheskikh Soedinenii, 1984 , vol. 20, # 6 p. 761 - 764
参考文献
Huang, Zhongyan; Xu, Jiaxi
RSC Advances, 2013 , vol. 3, # 35 p. 15114 - 15120
反应条件
1: carbon disulfide; sodium ethanolate in tetrahydrofuran
T=20°C; 0.5 h;
2: 2-bromo-4'-methoxy-acetophenone in tetrahydrofuran
1 h;
参考文献
Dehmel, Florian; Weinbrenner, Steffen; Julius, Heiko; Ciossek, Thomas; Maier, Thomas; Stengel, Thomas; Fettis, Kamal; Burkhardt, Carmen; Wieland, Heike; Beckers, Thomas
Journal of Medicinal Chemistry, 2008 , vol. 51, # 13 p. 3985 - 4001
反应条件
T=20°C; 0.216667 h; Ionic liquid;
参考文献
Gupta, Pankaj; Rouf, Abdul; Shah, Bhahwal A.; Mukherjee, Debaraj; Taneja, Subhash C.
Synthetic Communications, 2013 , vol. 43, # 4 p. 505 - 519
反应条件
potassium carbonate in N,N-dimethyl-formamide
T=20°C;
参考文献
Wang, You-Qing; Lu, Sheng-Mei; Zhou, Yong-Gui
Organic Letters, 2005 , vol. 7, # 15 p. 3235 - 3238
反应条件
1: 98 percent / ethanol / 2 h / Heating
2: 62 percent / HBr / diethyl ether / 2 h / 20 °C
View Scheme
参考文献
Delbecq, Frederic; Cordonnier, Guy; Pommery, Nicole; Barbry, Didier; Henichart, Jean-Pierre
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 5 p. 1119 - 1121
反应条件
1: Te / Heating
2: aq. Na2S2O5 / CH2Cl2
View Scheme
参考文献
Chauhan, Ashok K.S.; Kumar, Arun; Srivastava, Ramesh C.; Beckmann, Jens; Duthie, Andrew; Butcher, Ray J.
Journal of Organometallic Chemistry, 2004 , vol. 689, # 2 p. 345 - 351
反应条件
1: sodium hydrogencarbonate / ethanol / 5 h / |Reflux
2: trichlorophosphate / 1.5 h / 0 - 80 °C
View Scheme
参考文献
Kamal, Ahmed; Reddy, Vangala Santhosh; Karnewar, Santosh; Chourasiya, Sumit S.; Shaik, Anver Basha; Kumar, G. Bharath; Kishor, Chandan; Reddy, M. Kashi; Narasimha Rao; Nagabhushana, Ananthamurthy; Ramakrishna, Kallaganti V. S.; Addlagatta, Anthony; Kotamraju, Srigiridhar
ChemMedChem, 2013 , vol. 8, # 12 p. 2015 - 2025
反应条件
1: 89 percent / NaOEt / ethanol / 20 °C
2: 56 percent / AcOH; aq. HCl / 20 °C
3: 69 percent / Heating
View Scheme
参考文献
Maeda, Yutaka; Nakano, Masato; Sato, Hideyuki; Miyazaki, Yasushi; Schweiker, Stephanie L.; Smith, Jeffery L.; Truesdale, Anne T.
Bioorganic and Medicinal Chemistry Letters, 2004 , vol. 14, # 15 p. 3907 - 3911
反应条件
1: sodium azide; potassium iodide / water; acetonitrile / 1 h / 60 °C / |Green chemistry
2: magnesium sulfate; Rhodococcus ruber DSM 44541 alcohol dehydrogenase / isopropyl alcohol; aq. phosphate buffer / 20 h / 30 °C / pH 7 / |Autoclave; |Green chemistry; |Enzymatic reaction
3: hydrogen; sodium hydroxide / water; aq. phosphate buffer / 4 h / 30 °C / 7500.75 Torr / pH 9 / |Green chemistry
View Scheme
参考文献
Schrittwieser, Joerg H.; Coccia, Francesca; Kara, Selin; Grischek, Barbara; Kroutil, Wolfgang; D'Alessandro, Nicola; Hollmann, Frank
Green Chemistry, 2013 , vol. 15, # 12 p. 3318 - 3331
