2-甲基-1-苯并呋喃-7-胺盐酸盐合成路线 （共 4 条）
反应条件
hydrogen; palladium on activated charcoal in tetrahydrofuran; ethanol Yield given;
参考文献
SUN PHARMA ADVANCED RESEARCH COMPANY LTD.; THENNATI, Rajamannar; SAMANTA, Biswajit; PAL, Ranjan Kumar; KUMBHANI, Anil Savajibhai; ADHYAPAK, Jay Prakashchandra; AKOLKAR, Nakul P; PARMAR, Pravin; DUBEY, Megha
Patent: WO2013/88452 A2, 2013 ;
Location in patent: Page/Page column 71-72 ;
反应条件
sodium hydrogencarbonate in dichloromethane; water
参考文献
JACKSON, Paul Francis; Tounge, Brett Andrew; Leonard, Kristi Anne; Zhang, Yan; Wang, Aihua; Hawkins, Michael; Maharoof, Umar S.M.; Barbay, Joseph Kent
Patent: US2012/129842 A1, 2012 ;
Location in patent: Page/Page column 45 ;
反应条件
1: 1.5 h / 220 °C / |Inert atmosphere 2: tin(ll) chloride; hydrogenchloride / water; methanol / 0.5 h / 75 °C View Scheme
参考文献
SUN PHARMA ADVANCED RESEARCH COMPANY LTD.; THENNATI, Rajamannar; SAMANTA, Biswajit; PAL, Ranjan Kumar; KUMBHANI, Anil Savajibhai; ADHYAPAK, Jay Prakashchandra; AKOLKAR, Nakul P; PARMAR, Pravin; DUBEY, Megha
Patent: WO2013/88452 A2, 2013 ;
反应条件
1.1: potassium carbonate / N,N-dimethyl-formamide / 0.25 h / 20 °C 1.2: 0.5 h / 65 °C 2.1: 1.5 h / 220 °C / |Inert atmosphere 3.1: tin(ll) chloride; hydrogenchloride / water; methanol / 0.5 h / 75 °C View Scheme
参考文献
SUN PHARMA ADVANCED RESEARCH COMPANY LTD.; THENNATI, Rajamannar; SAMANTA, Biswajit; PAL, Ranjan Kumar; KUMBHANI, Anil Savajibhai; ADHYAPAK, Jay Prakashchandra; AKOLKAR, Nakul P; PARMAR, Pravin; DUBEY, Megha
Patent: WO2013/88452 A2, 2013 ;
