1,2-苯并异噻唑-3-酮合成路线 （共 63 条）
参考文献
Bristol-Myers Company
Patent: US4590196 A1, 1986 ;
US 4590196 A
反应条件
chromium(VI) oxide; periodic acid in acetonitrile T=20°C; 2.5 h;
参考文献
Journal of Organic Chemistry, , vol. 68, # 13 p. 5388 - 5391
参考文献
Chemische Berichte, , vol. 61, p. 1312
反应条件
copper(l) iodide; potassium carbonate; N-methyl-2-(methylamino)ethylamine in 1,4-dioxane T=195°C; 0.116667 h; Microwave irradiation;
参考文献
Liu, Dazhi; Tian, Zhen; Yan, Zhihui; Wu, Lixin; Ma, Yan; Wang, Quan; Liu, Wei; Zhou, Honggang; Yang, Cheng
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 11 p. 2960 - 2967
反应条件
potassium carbonate in tetrahydrofuran T=20 - 25°C; 2 h;
参考文献
Liu, Dazhi; Tian, Zhen; Yan, Zhihui; Wu, Lixin; Ma, Yan; Wang, Quan; Liu, Wei; Zhou, Honggang; Yang, Cheng
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 11 p. 2960 - 2967
反应条件
potassium carbonate in acetonitrile
T=20°C; 2 h;
参考文献
ROHM AND HAAS COMPANY; DOW GLOBAL TECHNOLOGIES LLC; STEPHENS, Randall W.; EMONDS, Mark V. M.; HENTON, Daniel R.
Patent: WO2014/85138 A1, 2014 ;
Location in patent: Page/Page column 5 ;
反应条件
sodium hydroxide in dimethyl sulfate
参考文献
Kajiwara, Masahiro
Patent: US2003/60482 A1, 2003 ;
反应条件
potassium carbonate in tetrahydrofuran
T=20 - 25°C; 2 h;
参考文献
Liu, Dazhi; Tian, Zhen; Yan, Zhihui; Wu, Lixin; Ma, Yan; Wang, Quan; Liu, Wei; Zhou, Honggang; Yang, Cheng
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 11 p. 2960 - 2967
反应条件
potassium carbonate
T=158°C; 7 h; Sealed tube; Temperature;
参考文献
ROHM AND HAAS COMPANY; DOW GLOBAL TECHNOLOGIES LLC; STEPHENS, Randall W.; EMONDS, Mark V. M.; HENTON, Daniel R.
Patent: WO2014/85138 A1, 2014 ;
Location in patent: Page/Page column 4 ;
反应条件
copper(l) iodide; potassium carbonate; N-methyl-2-(methylamino)ethylamine in 1,4-dioxane
T=195°C; 0.116667 h; Microwave irradiation;
参考文献
Liu, Dazhi; Tian, Zhen; Yan, Zhihui; Wu, Lixin; Ma, Yan; Wang, Quan; Liu, Wei; Zhou, Honggang; Yang, Cheng
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 11 p. 2960 - 2967
