1.1: potassium iodide; magnesium chloride / tetrahydrofuran / 1.5 h / 40 °C 1.2: pH 2.5 / Cooling with ice 2.1: 4-(N,N-dimethlyamino)pyridine; N-ethyl-N,N-diisopropylamine / pyridine / 1 h / 0 - 20 °C 3.1: triethylammonium formate; 1,1'-bis(diphenylphosphino)ferrocene / palladium diacetate / N,N-dimethyl-formamide / 8 h / 50 °C / Inert atmosphere 4.1: sodium hydroxide / water / 0.5 h / 30 °C 4.2: pH 7 View Scheme

1: 80 percent / methyl sulfoxide, trifluoroacetic anhydride, triethylamine / -70 °C 2: NaBH4 / tetrahydrofuran View Scheme