7-氨基去乙酰氧基头孢烷酸合成路线 （共 21 条）
反应条件
indium; potassium iodide in tetrahydrofuran; water T=60°C; Reduction; 4 h; Title compound not separated from byproducts;
参考文献
Chae, Hyungsun; Cho, Sangwon; Keum, Gyochang; Kang, Soon Bang; Pae, Ae Nim; Kim, Youseung
Tetrahedron Letters, 2000 , vol. 41, # 20 p. 3899 - 3901
反应条件
sodium hydroxide; glutaryl-7-aminocephalosporanic acid acylase in water T=25°C; pH=8.0; Enzymatic reaction; Enzyme kinetics;
参考文献
Rosini, Elena; Monelli, Claudia Stella; Pollegioni, Loredano; Riva, Sergio; Monti, Daniela
Journal of Molecular Catalysis B: Enzymatic, 2012 , vol. 76, p. 52 - 58
反应条件
1: KI; indium / H2O; tetrahydrofuran / 4 h / 60 °C 2: TMSCl; pyridine / 24 h View Scheme
参考文献
Chae, Hyungsun; Cho, Sangwon; Keum, Gyochang; Kang, Soon Bang; Pae, Ae Nim; Kim, Youseung
Tetrahedron Letters, 2000 , vol. 41, # 20 p. 3899 - 3901
反应条件
immobolised penicillin acylase Enzymatic reaction; Product distribution / selectivity;
参考文献
Rosini, Elena; Monelli, Claudia Stella; Pollegioni, Loredano; Riva, Sergio; Monti, Daniela
Journal of Molecular Catalysis B: Enzymatic, 2012 , vol. 76, p. 52 - 58
反应条件
sodium hydroxide in tetrahydrofuran Ambient temperature;
参考文献
Barrett,A.G.M.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1979 , p. 1629 - 1633
反应条件
triethylamine in dichloromethane Yield given. Title compound not separated from byproducts;
参考文献
Hendrix; Roets; Bervoets; Thomas; Pijcke; Busson; Janssen; Hoogmartens
Archiv der Pharmazie, 1994 , vol. 327, # 4 p. 215 - 219
反应条件
pyridine; phosphorus pentachloride in benzene 2 h; Ambient temperature; Yield given;
参考文献
Gruszecki, Wojciech; Gdulewicz-Gruszecka, Maria; Borowski, Edward
Polish Journal of Chemistry, 1980 , vol. 54, # 9 p. 1675 - 1679
反应条件
pyridine; phosphorus pentachloride in benzene 2 h; Ambient temperature; Yield given;
参考文献
Gruszecki, Wojciech; Gdulewicz-Gruszecka, Maria; Borowski, Edward
Polish Journal of Chemistry, 1980 , vol. 54, # 9 p. 1675 - 1679
反应条件
1: 89 percent / trimethylamine / dimethylsulfoxide / 20 h 2: 80 percent / pyridine monophosphoran / dioxane / 7 h / Heating 3: PCl5, pyridine / benzene / 2 h / Ambient temperature View Scheme
参考文献
Gruszecki, Wojciech; Gdulewicz-Gruszecka, Maria; Borowski, Edward
Polish Journal of Chemistry, 1980 , vol. 54, # 9 p. 1675 - 1679
反应条件
1: 95 percent / dimethylsulfoxide / 20 h / Ambient temperature 2: perbenzoic acid / CHCl3 / 1 h / 0 °C 3: 80 percent / pyridine monophosphoran / dioxane / 7 h / Heating 4: PCl5, pyridine / benzene / 2 h / Ambient temperature View Scheme
参考文献
Gruszecki, Wojciech; Gdulewicz-Gruszecka, Maria; Borowski, Edward
Polish Journal of Chemistry, 1980 , vol. 54, # 9 p. 1675 - 1679
