1: 95 percent / acetonitrile / 20 h / Heating 2: t-BuOK / tetrahydrofuran / -78 - 0 °C 3: 430 mg / H2 / Pd/C / ethyl acetate / 24 h / 25 °C View Scheme
参考文献
Hardouin, Christophe; Kelso, Michael J.; Romero, F. Anthony; Rayl, Thomas J.; Leung, Donmienne; Hwang, Inkyu; Cravatt, Benjamin F.; Boger, Dale L.
Journal of Medicinal Chemistry, 2007 , vol. 50, # 14 p. 3359 - 3368
1: t-BuOK / tetrahydrofuran / -78 - 0 °C 2: 430 mg / H2 / Pd/C / ethyl acetate / 24 h / 25 °C View Scheme
参考文献
Hardouin, Christophe; Kelso, Michael J.; Romero, F. Anthony; Rayl, Thomas J.; Leung, Donmienne; Hwang, Inkyu; Cravatt, Benjamin F.; Boger, Dale L.
Journal of Medicinal Chemistry, 2007 , vol. 50, # 14 p. 3359 - 3368
1: 27 g / KOH, KI / H2O; benzene / 2 h / Heating 2: NaOH, N2H4*H2O / methanol / 44 h / Heating View Scheme
参考文献
Blanchetiere, D.; Noyere, C.; Catel, J.; Andrieu, C. G.; Ebel, M.
Phosphorus, Sulfur and Silicon and the Related Elements, 1994 , vol. 91, # 1-4 p. 93 - 102
