1: 1-chloro-3-benzyloxypropane With magnesium in tetrahydrofuran
Heating;
2: (R)-3-(tert-butyldimethylsilyloxy)-2-methylpropyl triflate With dilithium tetrachlorocuprate in tetrahydrofuran
T=-20°C; 15 h;
3: With hydrogenchloride in methanol
T=20°C; 0.5 h; Further stages.;
参考文献
Herber, Christian; Breit, Bernhard
European Journal of Organic Chemistry, 2007 , # 21 p. 3512 - 3519