2,4-二氯吡啶合成路线

参考文献

The Dow Chemical Company
Patent: US4371537 A1, 1983 ;

参考文献

Woods, S. G.; Matyas, B. T.; Vinogradoff, A. P.; Tong, Y. C.
Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 1 p. 97 - 101

26452-80-22,4-二氯吡啶

73027-79-94,6-二氯烟酸

参考文献

Marzi, Elena; Bigi, Anna; Schlosser, Manfred
European Journal of Organic Chemistry, 2001 , # 7 p. 1371 - 1376

26452-80-22,4-二氯吡啶+

124-41-4甲醇钠

72141-44-72-甲氧基-4-氯吡啶

参考文献

Campeau, Louis-Charles; Dolman, Sarah J.; Gauvreau, Danny; Ouellet, Stephane G.; O'Shea, Paul D.; Corley, Ed; Liu, Jinchu; Guidry, Erin N.; Steinhuebel, Dietrich; Weisel, Mark
Organic Process Research and Development, 2011 , vol. 15, # 5 p. 1138 - 1148

26452-80-22,4-二氯吡啶+

100-51-6苯甲醇

1006052-55-6

参考文献

Micale, Nicola; Ettari, Roberta; Lavecchia, Antonio; Di Giovanni, Carmen; Scarbaci, Kety; Troiano, Valeria; Grasso, Silvana; Novellino, Ettore; Schirmeister, Tanja; Zappala, Maria
European Journal of Medicinal Chemistry, 2013 , vol. 64, p. 23 - 34

26452-80-22,4-二氯吡啶

1186647-69-74-氯-3-碘-1H-吡唑[4,3-c]吡啶

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MEDICAL RESEARCH COUNCIL TECHNOLOGY; GENENTECH INC.; CHAN, Bryan; CHEN, Huifen; ESTRADA, Anthony; SHORE, Daniel; SWEENEY, Zachary; McIVER, Edward
Patent: WO2012/38743 A1, 2012 ;
WO 2012/038743 A1

26452-80-22,4-二氯吡啶+

68-12-2N,N-二甲基甲酰胺

134031-24-62,4-二氯烟醛

参考文献

Khoje, Abhijit Datta; Gundersen, Lise-Lotte
Tetrahedron Letters, 2011 , vol. 52, # 4 p. 523 - 525

2591-86-8哌啶-1-甲醛+

26452-80-22,4-二氯吡啶

134031-24-62,4-二氯烟醛

参考文献

MEDICAL RESEARCH COUNCIL TECHNOLOGY; GENENTECH INC.; CHAN, Bryan; CHEN, Huifen; ESTRADA, Anthony; SHORE, Daniel; SWEENEY, Zachary; McIVER, Edward
Patent: WO2012/38743 A1, 2012 ;
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WO 2012/038743 A1

26452-80-22,4-二氯吡啶

134031-24-62,4-二氯烟醛

参考文献

Neubert, Timothy Donald; Piotrowski, David Walter; Walker, Michael Paul
Patent: US2004/44040 A1, 2004 ;

26452-80-22,4-二氯吡啶

1186194-98-8

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WO2012/62752 A1, ;
WO 2012/062752 A1