2,3-二氢-1H-茚-1-羧酸甲酯合成路线 （共 20 条）
反应条件
sodium hydroxide 2 h; Heating;
参考文献
Nongrum, F.M.; Myrboh, B.
Synthesis, 1987 , # 9 p. 845 - 846
反应条件
cyclohexane Erhitzen des Reaktionsprodukts mit Schwefel in Decalin;
参考文献
Treibs
Justus Liebigs Annalen der Chemie, 1957 , vol. 603, p. 145,153
反应条件
1: (indan-2-yl)-carboxylic acid With sulfuryl dichloride in dichloromethane
T=20°C; 0.583333 h;
2: methanol in dichloromethane
T=20°C; 3 h;
参考文献
MERCK and CO., INC.
Patent: WO2009/108550 A1, 2009 ;
Location in patent: Page/Page column 31 ;
WO 2009/108550 A1
反应条件
hydrogenchloride in diethyl ether; toluene
T=110°C; 3 h; Inert atmosphereSealed tube;
参考文献
Mitcheltree, Matthew J.; Konst, Zef A.; Herzon, Seth B.
Tetrahedron, 2013 , vol. 69, # 27-28 p. 5634 - 5639
反应条件
hydrogen; palladium on activated charcoal in methanol
T=20°C; 16 h;
参考文献
Takahashi, Tamiko; Kameda, Hiroaki; Kamei, Tomoyo; Ishizaki, Miyuki
Journal of Fluorine Chemistry, 2006 , vol. 127, # 6 p. 760 - 768
反应条件
[NiI2(PPh3)] in dichloromethane
T=40°C; Negishi coupling; 4 h;
参考文献
Deng, Ruixue; Sun, Liangdong; Li, Zhi
Organic Letters, 2007 , vol. 9, # 25 p. 5207 - 5210
反应条件
1: H2 / Pd/C / ethanol / 24 h / 2327.17 Torr
2: SOCl2 / CH2Cl2 / 0.75 h
3: 2.05 g / CH2Cl2 / 3 h
View Scheme
参考文献
Katz, Christopher E.; Aube, Jeffrey
Journal of the American Chemical Society, 2003 , vol. 125, # 46 p. 13948 - 13949
反应条件
methanol; sulfuric acid
Reflux;
参考文献
Pietruszka, Joerg; Simon, Robert Christian; Kruska, Fabian; Braun, Manfred
European Journal of Organic Chemistry, 2009 , # 35 p. 6217 - 6224
反应条件
lead(IV) acetate; boron trifluoride diethyl etherate in benzene
12 h; Ambient temperature;
参考文献
Nongrum, F.M.; Myrboh, B.
Synthesis, 1987 , # 9 p. 845 - 846
反应条件
lead(IV) acetate; boron trifluoride diethyl etherate in benzene
30 h; Ambient temperature;
参考文献
Cekovic, Z.; Bosnjak, J.; Cvetkovic, M
Tetrahedron Letters, 1980 , vol. 21, p. 2675 - 2678
